Comparación de la efectividad del midazolam en niños: via oral y via intranasal

Jerí, Esmeralda Soledad Castro; Díaz-Pizán, María Elena; Machuca, Mónica Valdivieso Vargas

doi:10.20453/reh.v15i2.1946

Cited by 5 publications

(8 citation statements)

References 10 publications

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“…Onset of sedative effects was reached around 30 minutes after oral midazolam administration, with both the 15 mg and 30 mg doses. In line with our observations, Castro et al . administered 0.5 mg/kg of oral midazolam to 10 children and found that onset of sedative effects was reached 30 minutes after administration .…”

Section: Discussionsupporting

confidence: 94%

“…In line with our observations, Castro et al . administered 0.5 mg/kg of oral midazolam to 10 children and found that onset of sedative effects was reached 30 minutes after administration . At no time in the present study did saturation level drop below 90%, the minimum accepted saturation level in the clinical setting.…”

Section: Discussionsupporting

confidence: 94%

“…Oral midazolam, a benzodiazepine, has been used successfully in accident and emergency medicine since 1992, and there are numerous studies on its use as premedication . Indications for conscious sedation include moderate mental and psychological disorders, such as DS, and it is often indicated for children undergoing dental treatment …”

Section: Discussionmentioning

confidence: 99%

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Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder

Ferrary

Ratto

Martínez

et al. 2019

Special Care in Dentistry

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Down syndrome (DS) presents with prevalent diseases in the oral cavity and the need of constant dental care and follow‐up. The use of conscious sedation (CS) for dental care in adult DS with behavioral disorders is poorly documented. The aim of this study was to evaluate the effectiveness and safety of CS procedures with oral midazolam using previous psychoprophylaxis sessions in DS adult patients with behavioral disorders. Methods: Twenty‐nine DS adults with behavioral disorders. The patients were managed with psychoprophylaxis followed by oral CS using 15 or 30 mg midazolam. Vital parameters were monitored. The Houpt and Brietkopf and Buttner scales were used. Results: Patients under CS received an initial dose of 15 mg midazolam; however, 51.72% needed a 30 mg dose at the following sessions. Results showed that 71.4% treated with the 15 mg dose had Houpt scale overall behavior scores of 4 or 5, while 93.33% of those receiving 30 mg had scores of 5 or 6 (chi‐square = 15.95 p < .01). Conclusion: Psychoprophylaxis sessions followed by CS procedures using oral midazolam in adult DS with behavioral disorders were shown to be a useful strategy to perform routine dental treatment safely. Midazolam produces anterograde amnesia, and participants were more cooperative in the following visits.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 94%

See 1 more Smart Citation

Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder

Ferrary

Ratto

Martínez

et al. 2019

Special Care in Dentistry

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show abstract

“…Por lo tanto, la concentración del midazolam en plasma podría haber sido mayor en menos tiempo del que se esperó (20 minutos). Por ello, en las fases posteriores se observaron valores cercanos para ambos grupos, e incluso durante el tratamiento el grupo 2 (jugo) mostró valores más favorables al alcanzar su mayor concentración plasmática (18,19 (22). En cambio, las investigaciones que compararon el midazolam oral y un placebo, siempre encontraron diferencias signifi cativa en la reducción de la ansiedad (10,23,24).…”

Section: Resultsunclassified

“…Los tiempo de recuperación obtenidos en ambos grupos se aproximan a los resultados de Castro et al, quienes encontraron un tiempo de recuperación promedio del midazolam oral (0,5mg/kg) de 108,1 minutos (95-120 minutos) (22).…”

Section: Resultsunclassified

Aceptabilidad y eficacia del midazolam oral en jugo y en gelatina en la sedación consciente de pacientes pre-escolares para su atención estomatológica

Tapia¹,

Vilcapoma²,

Núñez³

2017

Rev Estomatol Herediana.

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Aceptabilidad y eficacia del midazolam oral en jugo y en gelatina en la sedación consciente de pacientes pre-escolares para su atención estomatológica RESUMENObjetivos: Comparar la aceptabilidad y efi cacia del midazolam por vía oral (en gelatina y en jugo) en la sedación consciente de pacientes preescolares para su atención estomatológica. Material y métodos: Se incluyeron 50 niños sanos, no colaboradores, preescolares y con necesidad de atención estomatológica bajo sedación consciente quienes fueron asignados al azar a la preparación de midazolam vía oral (0,5mg/kg): jugo o gelatina. Se registraron la aceptabilidad del paciente, puntuaciones de conducta, signos vitales, efectos adversos y tiempo de recuperación. La medicación aplicada fue cegada al operador y al observador. Resultados: La aceptabilidad del midazolam usando gelatina fue signifi cativamente mayor (88%) que usando jugo (56%) (p<0,05). Las puntuaciones de conducta en cada parámetro (llanto, somnolencia, movimiento y comportamiento general) no difi eren en ambas vías de manera signifi cativa. Los valores de los signos vitales tuvieron parámetros normales para ambos grupos (en cada etapa de la sedación). No se identifi caron reacciones adversas en los grupos de estudio. La recuperación promedio para el grupo sedado con midazolam en jugo fue de 117 minutos y para el grupo sedado con midazolam en gelatina fue de 114,24 minutos. Conclusiones: El midazolam administrado por vía oral en jugo y en gelatina es efi caz en el tratamiento estomatológico bajo sedación consciente en niños no colaboradores en edad preescolar. Se destaca el uso del midazolam administrado en gelatina por la mayor aceptabilidad del paciente.

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Sedation of Pediatric Patients for Dental Procedures: The United States, European, and South American Experience

Wilson

Hosey

Costa

2014

Pediatric Sedation Outside of the Operating Room

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The challenges of sedating a child for dental procedures are multifactorial: The patient's age, health, temperament and emotional status, parental concerns, clinician philosophy on patient management, extent and quality of clinician training and experiences with sedation, state dental board regulation of sedation, issues of third-party coverage or parental reimbursement, knowledge of and adherence by clinicians to sedation guidelines, facility preparedness, and support staff experiences are but a few of many important considerations. To overcome these challenges, a pediatric dentist has to be at the hub of the preventive, operative and behavioral treatment plan.The fi rst section of this chapter is devoted to sedation practices performed primarily in the United States. The second section of this chapter describes sedation practices associated with the United Kingdom and Europe. The closing section will provide an overview of the state of sedation for pediatric dental procedures in South America, as an example of different solutions to sedation management in underdeveloped/developing countries.

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Comparación de la efectividad del midazolam en niños: via oral y via intranasal

Cited by 5 publications

References 10 publications

Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder

Psychoprophylaxis for oral conscious sedation for dental care in Down syndrome adults with behavioral disorder

Aceptabilidad y eficacia del midazolam oral en jugo y en gelatina en la sedación consciente de pacientes pre-escolares para su atención estomatológica

Sedation of Pediatric Patients for Dental Procedures: The United States, European, and South American Experience

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