“…6,8,9,29,34 Conversely, the other trials 11,12,24,30-32 used standardized scales (eg, FLACC, SEM, Visual Analogue and Verbal scale, Frankl scale, 33 and Wong Baker Faces Pain scale), increasing the reliability of their results due to their unbiased outcomes. The majority of trials 8,10-12, 24,25,27,29,31,34,35 obtained ethical approval from their respective institutes or at least signed informed consent by the child's parent or guardian. 6,9,28 However, four trials 7,30,32,41 did not clearly mention any ethical related issues, which may have affected the confidence toward their methodologies and results.…”