Comparative adaptogenic properties of Withania somnifera and Panax ginseng

Abstract

Adaptogens are natural (herbs) or synthetic compounds (levamisole) used to maintain stability in human body. The plant based adaptogens were mainly used to enhance the physical endurance and metal health of patients. However, adaptogens are widely studied for their ability to protect and cope up the body against physical, chemical and biological stress and related diseases. Panax ginseng and Withania somnifera are natural adaptogens, used to attenuate stress & related disorders without increasing oxygen consumption. This review deals with a detailed description of adaptogenic potential of Panax ginseng and Withania somnifera in improving human health. It also focuses on the similarity and mechanism of action of Panax ginseng and Withania somnifera as adaptogens on human stress induced disorders.

Influence and distribution of lead nitrate on growth and secondary metabolite accumulation in Withania somnifera (L.) Dunal in vitro shoots

“…HPTLC analysis was performed in the current study to quantify withaferin A content in the methanol extract of Pb(NO 3 ) 2 treated in vitro shoots of W. somnifera. One of the important secondary metabolites in W. somnifera is withaferin A has higher pharmaceutical value than other withanolides (Natarajan et al, 2022). Pb treatment was positively correlated with withaferin A content till a specific concentration.…”

“…Several specific reactions operating communally are responsible for the production of secondary metabolites in plants (Mansoori et al, 2020). The medicinal value of these secondary metabolites is due to the presence of reactive components that produce a definite biochemical reaction in humans (Natarajan et al, 2022). Flavonoids comprise the most common group of plant polyphenols and provide much of the flavour and colour to fruits, vegetables and have potent antioxidant and free-radical scavenging activities.…”

Exploring Transdermal Delivery of Traditional Herbal Medicine for Central Nervous System Disorders

“… Minimal Side Effects: Herbal remedies often have fewer side effects compared to pharmaceutical drugs. This makes them a safer option for some individuals, especially when dealing with milder conditions or symptoms [37].…”