Comparative analysis of calcium hydroxide apexification and regenerative endodontic procedure for root dentine growth stimulation in immature incisors with pulp necrosis

Рахманова, М. С.; Korolenkova, M V

doi:10.17116/stomat20209906155

Cited by 4 publications

(1 citation statement)

References 12 publications

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“…Searching study registries was not specified in the protocol common to a whole set of systematic reviews aiming to provide the basis of an ESE guideline. Also as specified in the protocol one study was excluded during full‐text review due to not being published in English language (Rakhmanova & Korolenkova, 2020). We did not provide quantitative syntheses for individual outcomes due to the small number of studies and their high heterogeneity.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review

2022

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Background: Regenerative endodontics has evolved in recent years with tissue engineering concepts in particular appearing promising. Endodontic tissue engineering (ETE) describes the various approaches based on the orthograde introduction of scaffolds or biomaterials (with or without cells) into the root canal to achieve pulp tissue regeneration. There are currently no systematic reviews investigating whether ETE is a suitable method for the treatment of endodontic disease in both mature and immature permanent teeth. Objectives:The purpose of this systematic review was to determine the effectiveness of ETE in permanent teeth with pulp necrosis in comparison with conventional endodontic treatment. Methods:We searched MEDLINE, Embase and the Cochrane Library for published reports as well as Google Scholar for grey literature up to November 2021. Included were studies of patients with permanent immature or mature teeth and pulp necrosis with or without signs of apical periodontitis (P) comparing ETE (I) with calcium hydroxide apexification, apical plug and root canal treatment (C) in terms of tooth survival, pain, tenderness, swelling, need for medication (analgesics and antibiotics), radiographic evidence of reduction in apical lesion size, radiographic evidence of normal periodontal ligament space, function (fracture and restoration longevity), the need for further intervention, adverse effects (including exacerbation, restoration integrity, allergy and discolouration), oral health-related quality of life (OHRQoL), presence of sinus tract and response to sensibility testing (O). An observation period of at least 12 months was mandatory (T) and the number of patients in human experimental studies or longitudinal observational studies had to be at least 20 (10 in each arm) at the end (S). Risk of bias was appraised using the Cochrane risk-of-bias (RoB 2) tool. Two authors independently screened the records, assessed full texts for eligibility and evaluated risk of bias. Heterogeneity of outcomes and limited body of evidence did not allow for meta-analysis.Results: Two randomized clinical trials investigating cell transplantation approaches with a total of 76 participants (40 treated immature teeth and 36 treated mature teeth) were included for qualitative analysis. Both studies had moderate

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Section: Discussionmentioning

confidence: 99%

Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review

2022

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Modern approach to the treatment of children with constant teeth avulsion

Korolenkova

Старикова

Рахманова

2020

Stomat.

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Results of “proroot mta” application in treatment of chronic periodontitis in teeth with incomplete root formation

Korneeva¹,

Novikova²,

Popova³

et al. 2022

Stomatol. vseh

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Based on the literature data, the article analyzes the features of the morphological structure of the endodontic teeth with incomplete root formation, pathomorphological characteristics of the development of periodontal inflammation in children and the features of the tactics of conservative endodontic treatment of chronic periodontitis. In detail discussed methods of treatment aimed at the formation of a barrier separating the lumen of the canal and the periodontium, the main of which is apexification. The technique of apexification using calcium hydroxide Ca(OH)2 and mineral trioxide aggregate (MTA), as well as the technique of revascularization or regeneration of pulp-like tissue (RPT), their advantages, limitations and possible complications are considered. Indications are formulated for choosing a particular treatment method. The features of the application of the discussed methods are illustrated by a clinical case.

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Comparative analysis of calcium hydroxide apexification and regenerative endodontic procedure for root dentine growth stimulation in immature incisors with pulp necrosis

Cited by 4 publications

References 12 publications

Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review

Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review

Modern approach to the treatment of children with constant teeth avulsion

Results of “proroot mta” application in treatment of chronic periodontitis in teeth with incomplete root formation

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