Among the sports injuries of long-distance runners, knee joint injuries are relatively common. According to the data, knee joint injuries account for about 25% of all kinds of sports injuries, ranking the first among all kinds of sports injuries. As to the cause and mechanism of injury, the most common injuries in this area are bone cartilage injury, meniscus injury, patellar fracture, collateral ligament and cruciate ligament injury. However, there are few studies on the compressibility fracture of tibial condyle and external condyle, so it is essential for long-distance runners to carry out regular training with correct technical specifications. The purpose of this paper is to solve the problem of the occurrence and development of the treatment of the compression fracture of the tibial condyle in long-distance runners. By studying the causes and mechanisms of the injuries, the causes and mechanisms of the injuries are analyzed and discussed. Scientific training methods and necessary preventive measures should be adopted to train more excellent athletes, to embody the effective value of this project for human body exercise. The results showed that the occurrence of the compression fracture of the tibial condyle of the knee joint was significantly related to the scientific nature of the training method, the intensity of the training and the length of time. Compared with traditional medical treatment, the new treatment in this paper can improve the curative effect by 30%. In the later rehabilitation training, I could improve my physical quality as soon as possible. The rehabilitation index of the patients with long-distance runners in the experiment increased by 20%, and the exercise development index increased by 12.5%.