Comparative analysis of electrochemical and optical sensors for detection of chronic wounds biomarkers: A review

Mota, Fátima A.R.; Passos, Marieta L.C.; Santos, João L.M.; Saraiva, M.Lúcia M.F.S.

doi:10.1016/j.bios.2024.116095

Cited by 8 publications

(3 citation statements)

References 148 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, they present some limitations, mainly related to their need for external energy sources. 117 Figure 3 contains a few representative examples of both electrochemical and optical polymeric MN-based sensors used for health and disease monitoring. Glucose monitoring plays a significant role in monitoring diseases (e.g., diabetes mellitus 118 and prediabetes 119 and gestational diabetes 120 ), and health conditions (e.g., insulinoma, 121 metabolic syndrome, 122 and Cushing’s syndrome 123 ).…”

Section: Current Trends Using Polymeric Microneedles For Monitoringmentioning

confidence: 99%

“…Electrochemical sensors are more common due to their cheap, easily reproducible and upscalable manufacture. However, they present some limitations, mainly related to their need for external energy sources Figure contains a few representative examples of both electrochemical and optical polymeric MN-based sensors used for health and disease monitoring.…”

Section: Current Trends Using Polymeric Microneedles For Monitoringmentioning

confidence: 99%

See 1 more Smart Citation

Polymeric Microneedles for Health Care Monitoring: An Emerging Trend

Pereira,

Vinayakumar,

Sillankorva

2024

ACS Sens.

View full text Add to dashboard Cite

Bioanalyte collection by blood draw is a painful process, prone to needle phobia and injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect analytes from the interstitial fluid, arising as a safe, painless, and effective alternative to hypodermic needles. Although there are plenty of reviews on the various types of microneedles and their use as drug delivery systems, there is a lack of systematization on the application of polymeric microneedles for diagnosis. In this review, we focus on the current state of the art of this field, while providing information on safety, preclinical and clinical trials, and market distribution, to outline what we believe will be the future of health monitoring.

show abstract

Section: Current Trends Using Polymeric Microneedles For Monitoringmentioning

confidence: 99%

Section: Current Trends Using Polymeric Microneedles For Monitoringmentioning

confidence: 99%

Polymeric Microneedles for Health Care Monitoring: An Emerging Trend

Pereira,

Vinayakumar,

Sillankorva

2024

ACS Sens.

View full text Add to dashboard Cite

show abstract

“…High sensitivity and the capacity to locate biomarkers in intricate biological contexts are among its advantages. 71 The most popular bioreceptors for detecting Salmonella are immunoglobulins, aptamers, antimicrobial peptides (AMPs), bacteriophages, and nucleic acid probes. Antibody biosensors have high affinity and specificity but they are poor in stability, expensive technique.…”

Section: Role Of Biosensors In the Detection Of Zoonotic Pathogensmentioning

confidence: 99%

Nanomaterials-Integrated Electrochemical Biosensors as Pioneering Solutions for Zoonotic Disease Diagnosis

Saklani,

Barsola,

Pathania

et al. 2024

J. Electrochem. Soc.

View full text Add to dashboard Cite

Zoonotic diseases are a pressing challenge to global health, arising from their interspecies transmission and potential for pandemics. Conventional diagnostic methodologies often suffer from limitations in speed, sensitivity, and accuracy, underscoring the imperative for innovative solutions. Nanomaterial-integrated biosensors, especially in electrochemical module have gained increasing attention as promising tools for the rapid, sensitive, point-of-care and targeted detection of zoonotic pathogens. Despite considerable progress, pervasive challenges, including market fragmentation and research disparities, impede widespread adoption. This review explores the essential role of electrochemical biosensors in combating zoonotic diseases, underscoring the urgency for accessible, cost-effective, and high-throughput diagnostic platforms. It details the principles of electrochemical biosensing and highlights the role of diversified nanomaterials in enhancing the performance of biosensors. Furthermore, it examines the integration of nanomaterials with different electrodes and signal amplification strategies to improve its sensing performance. It details the current challenges, alternate solutions and perspectives in the development and translation of these biosensors for point-of-care diagnosis/surveillance of zoonotic diseases. This review provides valuable insights into the potential of nanomaterial-based electrochemical biosensors to revolutionize the diagnosis and management of zoonotic diseases, ultimately contributing to global efforts to mitigate the impact of these contagious threats on human and animal health.

show abstract