2011
DOI: 10.1016/j.clinbiochem.2011.08.059
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Comparative analysis of essential oil composition of Iranian and Indian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) and Solvent Extraction

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Cited by 4 publications
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“…However, these methods have several drawbacks: they are time‐consuming, use polluting organic solvents and show low selectivity, which leads to their limited application in the food industry (Arnaiz et al, 2016). Moreover, these procedures also contribute to the denaturation due to high temperature during the extraction of some bioactive compounds that potentially act as antioxidant and antimicrobial agents (Latiff, Ghahramanloo, & Hanachi, 2017). One of the recent alternative green technologies that can overcome the limitation mentioned above is using the supercritical fluid extraction (SFE) approach.…”
Section: Introductionmentioning
confidence: 99%
“…However, these methods have several drawbacks: they are time‐consuming, use polluting organic solvents and show low selectivity, which leads to their limited application in the food industry (Arnaiz et al, 2016). Moreover, these procedures also contribute to the denaturation due to high temperature during the extraction of some bioactive compounds that potentially act as antioxidant and antimicrobial agents (Latiff, Ghahramanloo, & Hanachi, 2017). One of the recent alternative green technologies that can overcome the limitation mentioned above is using the supercritical fluid extraction (SFE) approach.…”
Section: Introductionmentioning
confidence: 99%
“…Five experimental rat groups were established with 8 rats per group. The groups were as follows: group 1, negative control (1 ml Olive Oil), group 2, positive control (0.2mg/kg/day CEE diluted in distilled water), group 3 Linoleic acid (daily 50 mg/kg LA which calculated based on yielding Nigella sativa fixed oil (29%) and concentration of LA (57%) in fixed oil), group 4, Thymoquinone (daily 15mg/kg TQ which calculated based on yielding Nigella sativa fixed oil (29%) and concentration of TQ (16.1%) in fixed oil which analyzed and reported by Latiff et al, 12 on the same plant source) and group 5, Gamma Linolenic acid (daily 10 mg/kg GLA which calculated based on yielding Nigella sativa fixed oil (29%) and concentration of GLA (2%) in fixed oil and probability of its production through conversion from LA). All ingredients were diluted in olive oil as vehicle.…”
mentioning
confidence: 99%