Comparative analysis of QCM and SPR techniques for the optimization of immobilization sequences

Novel fully-integrated biosensor for endotoxin detection via polymyxin B immobilization onto gold electrodes

“…SAMs are organized structures of organic molecules that allow the efficient and simple immobilization of different compounds used for biological detection (Pillay et al, 2009). Once SAMs are formed, they remain strongly attached to the surface through their terminal thiol group and provide a well-defined and stable interface for ligand immobilization (Ansorena et al, 2011).…”

Nylon nanoweb with TiO2 nanoparticles as a solid matrix for matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

“…First, the nylon nanowebs were prepared on the surface of the QCM sensors while using different spinning times, and the resonance frequency shift of the QCM sensor was measured from the initial value (10 MHz). The QCM sensor response was converted into the mass loading on the nanowebs through the Sauerbrey equation: Δf = –2⋅Δm⋅f 0 2 /[A⋅(μ q ⋅ρ q ) 1/2 ], where ρ q is the quartz density, μ q is the crystal shear module, f 0 is the fundamental crystal frequency, A is the active area of the crystal defined by the area of the deposited metallic film on the crystal, and Δm and Δf correspond to the mass of produced nanowebs and the frequency changes from the electrospinning and electrospraying process, respectively …”

“…The growth rate of the nylon nanoweb with TiO 2 nanoparticles was monitored using a QCM sensor that responded to the mass loading on the sensor surface. [25] First, the nylon nanowebs were prepared on the surface of the QCM sensors while using different spinning times, and the resonance frequency shift of the QCM sensor was measured from the initial value (10 MHz). The QCM sensor response was converted into the mass loading on the nanowebs through the Sauerbrey equation:…”

“…where ρ q is the quartz density, μ q is the crystal shear module, f 0 is the fundamental crystal frequency, A is the active area of the crystal defined by the area of the deposited metallic film on the crystal, and Δm and Δf correspond to the mass of produced nanowebs and the frequency changes from the electrospinning and electrospraying process, respectively. [25][26][27] Measurement of the photocatalytic activity…”

Determination of Peptide–Surface Adsorption Free Energy for Material Surfaces Not Conducive to SPR or QCM using AFM

“…21–23 Hence, while the use of methods such as SPR and QCM are readily amenable for use with SAMs on gold–coated sensor chips, 17, 24, 25 their use becomes problematic for a broad range of other common material surfaces that may need to be evaluated, therefore necessitating the development of alternative methods to quantitatively evaluate the adsorption behavior of peptides on surfaces of bulk material samples.…”