Space syntax is utilized to model flows through open and closed built environments, which enables project innovation by rethinking the design of spaces on a global scale with better flow quality. Therefore, studies focused on spatial syntax, when related to comprehensive flows in open and closed spaces, provide a holistic and valuable understanding of the dynamics of user flows in the urban environment from a perspective centered on the United Nation’s Sustainable Development Goal (SDG) 11. This goal requires urban planners and designers to use approaches that support future decisions focused on urban design and planning. The object of investigation of this bibliographic study consists of an approach to representing space syntax in open spaces and closed spaces on a global scale. This study aims to analyze the concepts of pedestrian flows (open and closed) by a space syntax-based bibliographical approach on a global scale, demonstrating the capability of improvements in SDG 11 as applied to the architecture of sustainable flows. Methodologically, bibliographic searches were carried out using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method in databases linked to Scopus and ScienceDirect, focusing on space syntax in relation to the following terms: “open spaces” and “closed spaces”. Using the PRISMA method, 1986 manuscripts dealing with the term “open spaces” and 454 manuscripts dealing with the term “closed spaces” were identified, with the manuscripts most relevant to the topic being selected, followed by a frequency analysis based on a Content Analysis Method (CAM) to identify words with a degree of similarity, related to “spatial syntax: flow in urban environments” and “spatial syntax in closed built systems” in relation to the SDG 11. The results demonstrate the relevance of seven manuscripts in open spaces and four manuscripts in closed spaces related to space syntax. Frequency analysis identified open spaces and produced terms with frequencies such as space = 79 and shape = 46, showing a higher frequency in flows. In closed spaces, the literature has shown that the central term corresponds to space = 79 and flow = 76, making it possible to evaluate flows in circulation areas within the built environment. This study allows a better understanding of flows, highlighting the importance of the urban architecture in the functionality of user flows in sustainable environments, which is capable of contributing to the SDG 11, in the interface of architectural projects on a global scale.