Comparative analysis of single-walled and multi-walled carbon nanotubes for electrochemical sensing of glucose on gold printed circuit boards

Alhans, Ruby; Singh, Anukriti; Singhal, Chaitali; Narang, Jagriti; Wadhwa, Shikha; Mathur, Ashish

doi:10.1016/j.msec.2018.04.072

Cited by 52 publications

(23 citation statements)

References 26 publications

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Section: Three Generations Of Enzymatic Glucose Sensorsmentioning

confidence: 99%

“…Cinti et al synthesised PB nanoparticles on a filter paper, using it to immobilise GOx allowing the sensing of glucose in blood samples [67]. Moreover, a wide range of nanomaterials including carbon nanotubes (CNTs) [68], Pt nanoparticles [69], and composite nanomaterials [70,71] were successfully used to improve selec- An alternative approach is the use of Prussian blue (PB) to minimise interference, for example, Kafi et al [65] fabricated a GOx/multiporous tinoxide nanofiber film on a PB-modified gold (Au) electrode for biosensing [65]. The aim was to develop a highly selective and low potential glucose biosensing, due to the PB having high catalytic activity and selectivity for the reduction of H 2 O 2 .…”

Section: First-generation Enzymatic Glucose Biosensorsmentioning

confidence: 99%

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Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Hassan

Vyas

Grieve

et al. 2021

Sensors

213

111

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The detection of glucose is crucial in the management of diabetes and other medical conditions but also crucial in a wide range of industries such as food and beverages. The development of glucose sensors in the past century has allowed diabetic patients to effectively manage their disease and has saved lives. First-generation glucose sensors have considerable limitations in sensitivity and selectivity which has spurred the development of more advanced approaches for both the medical and industrial sectors. The wide range of application areas has resulted in a range of materials and fabrication techniques to produce novel glucose sensors that have higher sensitivity and selectivity, lower cost, and are simpler to use. A major focus has been on the development of enzymatic electrochemical sensors, typically using glucose oxidase. However, non-enzymatic approaches using direct electrochemistry of glucose on noble metals are now a viable approach in glucose biosensor design. This review discusses the mechanisms of electrochemical glucose sensing with a focus on the different generations of enzymatic-based sensors, their recent advances, and provides an overview of the next generation of non-enzymatic sensors. Advancements in manufacturing techniques and materials are key in propelling the field of glucose sensing, however, significant limitations remain which are highlighted in this review and requires addressing to obtain a more stable, sensitive, selective, cost efficient, and real-time glucose sensor.

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Section: Three Generations Of Enzymatic Glucose Sensorsmentioning

confidence: 99%

Section: First-generation Enzymatic Glucose Biosensorsmentioning

confidence: 99%

Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Hassan

Vyas

Grieve

et al. 2021

Sensors

213

111

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“…Glucose detection is generally realized in electrochemical sensors that involve enzyme‐assisted amperometric processes by combining GOx with conductive materials such as conducting polymers, [ 240,241 ] carbon nanomaterials, [ 242–244 ] metal NPs, [ 245,246 ] and 2D materials beyond graphene. [ 247–249 ] The introduction of biocompatible hydrogels improves the immobilization and stabilization of GOx and the permeation of water‐soluble molecules, which facilitate the effective oxidation of glucose.…”

Section: Applications Of Composite Hydrogel‐based Biosensorsmentioning

confidence: 99%

Hydrogel‐based composites: Unlimited platforms for biosensors and diagnostics

Wang

Liu

Wang

et al. 2021

VIEW

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The need for biosensing systems, which are capable of reliable and accurate detection of physiological signals and disease biomarkers along with biocompatible surface chemistry and textures for device–human interface, has driven the continuous search for advanced sensing materials, sensing strategies, and device structures. Hydrogels are hydrophilic polymers with high water content and thus akin to human tissues. They are not only able to act as polymeric matrices to load functional materials for bio‐signal transducing, but also stimuli‐responsive to cooperate with the filler materials for further enhanced sensing performance. A vast combination of hydrogels and functional fillers such as biomacromolecules, metal nanostructures, carbon nanomaterials, and two‐dimensional materials beyond graphene has been demonstrated over the last decade for fabrication of biosensors for disease diagnosis and health monitoring. This review article aims to provide an overview of the various hydrogel‐based composites, introduce their preparation protocols, and describe the working principles of their corresponding sensors. Recent development of these sensors for potential diagnosis of diseases such as diabetes, cancers, and cardiovascular diseases is then summarized, followed by stating the current challenges and prospects in this field.

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“…Recently, electrochemical immunosensors have attracted huge attention owing to their unique advantages of rapid response, good sensitivity, convenient operation, and highly specific recognition between antigens and antibodies, which can quantitatively detect biomarkers [14][15][16]. Signal amplification in the electrochemical immunosensors can be achieved using specific advanced nanomaterials, such as graphene [17], carbon nanotubes, nanoporous materials [18,19], quantum dots [20], noble metal nanoparticle composite [21], and nanocomposite materials [22], including transition metal oxides, which have attracted significant attention for fabrication of electrochemical biosensors [5,23] because of their excellent electrochemical activities, good redox activity, high surface area, cost-effectiveness, and environmental compatibility.…”

Section: Introductionmentioning

confidence: 99%

Au@Zr-based metal–organic framework composite as an immunosensing platform for determination of hepatitis B virus surface antigen

et al. 2021

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An ultrasensitive electrochemical immunosensor has been prepared using an immunofunctionalized zirconium (Zr)-based metalorganic framework (MOF) with gold (Au) decoration Au@UiO-66(NH 2 ) composite-coated glassy carbon electrode (GCE) for the determination of infectious hepatitis B surface antigen (HBsAg). We fabricated GCE with specific composite via immunefunctionalization using anti-HBsAg with Au nanoparticles embedded in UiO-66(NH 2 ). The electrochemical sensing performance of the immunofunctionalized Au@UiO-66(NH 2 )/GCE with HBsAg was characterized by cyclic voltammetry and differential pulse voltammetry. Under optimized conditions, there was a linear dynamic relationship in the buffer system between the electrical signal and HBsAg levels over the range 1.13 fg mL −1 -100 ng mL −1 (R 2 = 0.999) with a detection limit of 1.13 fg mL −1 . The total analysis time was 15 min per sample. Further validations were performed with HBsAg-spiked human serum samples, and similar detection limits as in the buffer system were observed with reduced signal intensities at lower concentrations of HBsAg (1, 10, and 100 fg mL −1 ) and minimal interference. The HBsAg electrochemical immunosensing assay had good selectivity and excellent reproducibility, thereby indicating its significant potential in the super-fast diagnosis of hepatitis B.

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Comparative analysis of single-walled and multi-walled carbon nanotubes for electrochemical sensing of glucose on gold printed circuit boards

Cited by 52 publications

References 26 publications

Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Hydrogel‐based composites: Unlimited platforms for biosensors and diagnostics

Au@Zr-based metal–organic framework composite as an immunosensing platform for determination of hepatitis B virus surface antigen

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