The selection of an optimum location for the installation of a Concentrated Solar Power (CSP) plant is very vital to its overall performance. Any selected location should suitably satisfy some favourable selection criteria such as high direct normal irradiance, high ambient temperature, lower wind speed, lower level of cloud cover and availability of a source of water. In this paper, the selection of an optimal location(s) for a CSP plant in Ghana is achieved using the Analytical Hierarchy Process (AHP) for the weighting of the selected criteria and then using a set of Multi-Criteria Decision-Making (MCDM) methods for the ranking of the various alternatives. The MDCM methods used in this work include the Vise Kriterijumsa Optimizacija I Kompromisno Resenje (VIKOR), Technique for Order of Performance by Similarity to Ideal Solution (TOPSIS), and Complex Proportional Assessment (COPRAS). The results indicate that VIKOR and COPRAS gave very closely related rankings while some of the rankings for the COPRAS were not closely related as compared to the other two methods. However, all three methods ranked Bawku, a town in the Upper East region of Ghana, as the most suitable location for the installation of a CSP plant. The other suitable locations, i.e., Navrongo, Yendi, Wa, Bolgatanga and Savelugu, for the installation of a CSP plant are in the northern part of the country.