2023
DOI: 10.21203/rs.3.rs-2752899/v1
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Comparative analysis of tuberculin and defined antigen skin tests for the detection of bovine tuberculosis in buffaloes (Bubalus bubalis)

Abstract: Background: Bovine tuberculosis (bTB) is a chronic disease that results from infection with any member of the Mycobacterium tuberculosis complex and infected animals are typically diagnosed withtuberculin-based intradermal skin tests per World Organization of Animal Health or similar guidelines. Peptide-based defined skin test (DST) antigens, comprising of ESAT-6, CFP-10 and Rv3615c, are able to differentiate infected from BCG-vaccinated animals and sensitively and specifically identify tuberculin reactor catt… Show more

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