Comparative and Randomized Study of Rich-Platelet Plasma in Male Androgenetic
            Alopecia

Marques, Camila Carneiro; Steiner, Denise; Miquelin, Gabriela Momente; Colferai, Mariana Morais Tavares; Gatti, Eduardo Figueiredo

doi:10.5935/scd1984-8773.20168406

Cited by 15 publications

(4 citation statements)

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“…The system and accompanied software (SW) (Trichoscale Pro, Foto-Finder Systems GmbH, Germany) allows quantification and analysis of the diffused hair loss. The software is validated for MAGA [30] and automatically calculates number of hairs, mean HD (hairs/cm 2 ), terminal and vellus hair percentage, hair thickness, and number and density of follicular units -all within a standard 0.903 cm 2 area (1.07 cm diameter area). During SW evaluation, all hairs with thickness > 40.0 µm are described as terminal hairs, while hairs with lesser thickness are described as vellus hairs.…”

Section: Injection Proceduresmentioning

confidence: 99%

“…Platelet-rich plasma (PRP) and micrografts containing mesenchymal stem cells from hair follicles and adipose tissue have demonstrated hair regrowth in patients with androgenetic alopecia. Injection of PRP containing growth factors has been shown to improve hair count, hair thickness and hair density[30] [36]. The plasma is believed to promote hair differentiation and inhibit apoptosis of HF cells.…”

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confidence: 99%

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Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia

Naranjo

2024

JCDSA

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Introduction: Mechanism of male androgenic alopecia (MAGA) is complex and leads to an excessive hair shedding and decreased hair density. Oral, topical, and injectable autologous treatments demonstrate ability to stimulate hair re-growth, but the response is suboptimal or plateaus off. Synthetic combination of the peptide complex and hyaluronic acid (P-HA) demonstrated hair regrowth in alopecia patients. Electronically-operated pneumatic injections (EPI) generate micro-trauma in the dermis and under wound-healing conditions may enhance regeneration effect of P-HA. Methods: Subjects seeking improvement of their male pattern hair loss (Hamilton-Norwood type 2 -4) received the P-HA treatments through EPI. The course included 4 treatments every two weeks over the 8-week period. In 6 months, the hair growth was assessed comparative to baseline by global clinical photography and digital phototrichograms. The treatment safety and tolerability were documented through the whole study period. Results: Twelve men (30 -45 years old) completed the treatment course with high tolerability and without adverse events. Post-treatment assessment of the previously bald areas showed improved coverage on the clinical photographs. The phototrichograms demonstrated statistically significant increase in terminal hair density by 36%, cumulative hair thickness by 37%, and follicular units by 20%; all contributing to a 38% increase in cumulated hair density (all p < 0.05). Conclusion: Electronic pneumatic injections are well tolerated and can be safely used for the needle-free administration of the peptide-hyaluronic acid combination in MAGA therapy. We achieved significant hair re-densification in the balding scalp. The exact role of the EPI-induced impact in the hair re-growth mechanism remains to be ascertained.

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Section: Injection Proceduresmentioning

confidence: 99%

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confidence: 99%

Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia

Naranjo

2024

JCDSA

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“…O fracionamento é um processo para obtenção de concentrados de plaquetas a partir da centrifugação do sangue do próprio paciente (autóloga), seguida da extração da O PRP contém alguns leucócitos em seu interior, o que propicia uma resistência natural a processos infecciosos, reduzindo risco de infecções no local a ser tratado. Além disso, o PRP ativado, devido a seus efeitos anti-apoptóticos, aumenta a sobrevivência de células do folículo piloso e prolonga a fase anágena estimulando o crescimento capilar (MARQUES, et al, 2016).…”

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Ciências da saúde: bem-estar e qualidade de vida

Lauer

2023

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“…PRP contains some leukocytes inside, which provides natural resistance to infectious processes, reducing the risk of infections in the area being treated. Furthermore, activated PRP, due to its anti-apoptotic effects, increases the survival of hair follicle cells and prolongs the anagen phase, stimulating hair growth (MARQUES, et al, 2016).…”

Section: Prp Treatmentmentioning

confidence: 99%

Use of platelet-rich plasma in orthopedic treatments

Ribeiro,

Celestino

2023

JHS

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Platelet-rich plasma, a concentrate of blood platelets, has enormous potential in therapeutic modality due to several advantages. The volume of plasma found in PRP (platelet-rich plasma) has a concentration of platelets five times greater than that found in normal blood. It can be obtained through single or double centrifugation, it is extremely important that the PRP is always autologous, thus avoiding the risk of rejection. PRP has been applied in the most diverse areas: aesthetics, dentistry, regenerative medicine, biotechnology, ophthalmology and orthopedic treatments. It also manifests antiinflammatory properties, anabolic effects and gelling capacity. Through CF (growth factors) released by the platelets it contains, PRP assists in the processes of osteoinduction and osteointegration. Furthermore, studies reveal promising results in its use after total knee arthroplasty, as well as in other orthopedic treatments.

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Comparative and Randomized Study of Rich-Platelet Plasma in Male Androgenetic Alopecia

Cited by 15 publications

References 0 publications

Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia

Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia

Ciências da saúde: bem-estar e qualidade de vida

Use of platelet-rich plasma in orthopedic treatments

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