Comparative Assessment of the Analgesic Efficacy of Tramadol and Diclofenac Sodium Rectal Suppository in Subjects Undergoing Laproscopic Tubal Ligation

Abstract

Background: Several drugs such as NSAID s or opiods can be used orally, intravenously or intramuscularly for treatment of post operative pain. The aim of our study was to compare the analgesic efficacy of tramadol and diclofenac sodium suppository and the secondary aim was to monitor and treat the complications if any. Subjects and Methods: Fifty female patients of ASA I and II in the age group of 24-42 posted for laproscopic tubal ligation were enrolled in the study. Verbal analogue scale (0-no pain to 10-worst possible pain) score reading was explained. In the pre operative room all the patients were randomly allocated in two groups by a computer generated list. Post operatively all the hemodynamic parameters and VAS score were recorded at regular intervals of 1, 2, 4, 6, 8, 10,12hrs. Pain was assessed by a staff trained to VAS score assessment and was blinded to the study group. Side effects of nausea and vomiting were noted. Results: Group 2 had high mean age of the study participants compared to group 1 but the comparison was non-significant.(p≤0.05) Only one patient in group A (tramadol) complained of nausea and vomiting. In group A 69% patients needed 1 rescue analgesic at 8 hrs, 11% at 6hrs, 9% at 4hrs and 11% at 10 hrs whereas in group B 64.1% patients needed 1 rescue analgesic at 8hrs, 16.2% at 10 hrs and 19.7 % at12 hrs. Conclusion: From above findings it was concluded that analgesic efficacy of tramadol and diclofenac sodium suppository is comparable. Rectal administration of tramadol reduces the incidence of nausea and vomiting.

Effectiveness of Postoperative Analgesia with Rectal Placement of Diclofenac Sodium in Patients Undergoing Gynecological and Obstetrical Surgeries under General Anesthesia

“…Bakhsha F. et al found similar things concerning diclofenac sodium 12 suppositories in 2013. Among patients undergoing tubal ligation, Baranda UK et al (2019) found that 69 percent of those given tramadol required at least one rescue analgesic at 8 hours, 11 percent at 6 hours, 9 percent at 4 hours, and 11 percent at 10 hours, while 64 percent of those given diclofenac suppositories did so at 8 hours, 16 percent at 10 hours, and 19 13 percent at 12 hours. There have been several studies into how diclofenac sodium suppositories affect the need for pain relief after surgery.…”