Change in the structure of global commodity markets' demand for high-tech science-intensive digital technologies influence the existing structure of economies of raw material regions and form new requirements for the product portfolio of exports. One of the main trends of export regional potential is becoming the expansion of assortment due to high-tech products with a high share of added value in the economy of a region. However, the existing methodological approaches to the assessment of external demand of a region are not focused on achieving structural transformations of regional economy; the existing mechanisms of state support are mainly aimed at the interests of local businesses in the short-term period of development. The purpose of the article is to propose methods for the formation of export potential of regional economy on the basis of development of high-tech fields, new sectors and markets. A system-structure approach to research, which was developed by the authors, includes clarifying the concept of export potential, identifying the stages of its formation and development, determining the performance metrics of choosing marketable products to form a regional export potential, highlighting the direction of the development of the latter. Based on the comparative analysis of approaches to the assessment and development of a regional export potential, the authors formulated a basic premise to model its structure and level assessment: the requirement to distinguish between ways of revealing and assessing priority and long-range types of export products. A step-by-step methodology to form a regional export potential, which is aimed at selecting both priority types of existing export products and new types of promising high-tech products for the growth in regional exports on the global market, is proposed. As methods for selecting priority types of export products the authors used a structural dynamic analysis, a grouping method based on the XYZ-analysis and variation coefficients, a positioning method. To substantiate the choice of new types of promising products for the growth in regional exports on the global market, the following methods were used: intersection of sets, evaluation of the potential of global commodity markets and of a potential share of commodity position in regional exports, evaluation of comparative advantage of countries based on the Balassa index. Approbation of methods for forming a regional export potential is presented using the example of the Krasnoyarsk Territory.