Comparative benefit of two thermal spring waters after photodynamic therapy procedure

Goldman, Mitchel P.; Mérial-Kieny, C.; Nocera, Thérèse; Méry, Sophie

doi:10.1111/j.1473-2165.2007.00291.x

Cited by 31 publications

(25 citation statements)

References 15 publications

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“…In the present study, we observed a significant reduction in pain, cutaneous dryness, and redness/erythema in the TSW‐treated side of the face following fractional laser irradiation. These results are in line with previous studies showing the soothing and anti‐irritant properties of TSW in various skin conditions such as irritation secondary to topical retinoïc acid, and after specific procedures like ALA‐PDT 7,12,13 . TSW has also been shown to decrease local skin temperature, as measured by thermography after vascular laser treatment in patients suffering from rosacea 14 .…”

Section: Discussionsupporting

confidence: 91%

Beneficial effects of spraying low mineral content thermal spring water after fractional photothermolysis in patients with dermal melasma

Barolet

Lussier²,

Méry³

et al. 2009

J of Cosmetic Dermatology

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Section: Discussionsupporting

confidence: 91%

Beneficial effects of spraying low mineral content thermal spring water after fractional photothermolysis in patients with dermal melasma

Barolet

Lussier²,

Méry³

et al. 2009

J of Cosmetic Dermatology

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“…Thermal mineral water treatments have been demonstrated to promote healing of skin irritations (5) and to improve skin restoration after cosmetic aggressive procedures (6,7). Such effects are likely to be related to some anti-inflammatory action (8,9).…”

Section: Discussionmentioning

confidence: 99%

Effects of thermal water on skin regeneration

et al. 2012

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Abstract. An experimental study was carried out in an animal (New Zealand white rabbit) wound model to evaluate any effects of a hypotonic, bicarbonate-calcium-magnesium mineral water (Comano thermal water) on skin regeneration, comparing the healing rate of split-thickness skin graft donor sites treated with the thermal water wet dressing versus a standard petrolatum gauze dressing versus a saline solution wet dressing. The study was performed in two steps; an overall of 22 animals were enrolled in the study. The wound healing progress was evaluated both by the surgeons and by the histologists. Sixty-four punch biopsies were examined in all. The histological samples were examined after staining with haematoxylin and eosin, Masson's and orcein staining and under a transmission electron microscope. The data were statistically analysed. The Comano thermal water proved to improve skin regeneration, not only by increasing keratinocyte proliferation and migration but also favourably modulating the regenerated collagen and elastic fibres in the dermis. We propose that the results of the topical treatment with the thermal water could be due to the favourable combination of a local wet environment with an anti-inflammatory action and that the regenerative properties of Comano thermal water observed in rabbits could also be applied for human use.

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“…Pagliaro et al (Table III) investigated cold air anesthesia in ALA-PDT for BCC, finding a lower mean duration of pain compared to the ambient air group 72 . In twenty-one additional studies, some form of local cooling was also offered to the patients 5111525273038–434663666870717374 . Possible mechanisms for pain reduction include a reduction of tissue metabolism (thus reducing the effects of injury), and vasoconstriction, which would reduce the inflow of inflammatory mediators and thereby decrease edema.…”

Section: Pain Managementmentioning

confidence: 99%

Pain associated with aminolevulinic acid-photodynamic therapy of skin disease

Warren

Karai

Vidimos

et al. 2009

Journal of the American Academy of Dermatology

119

101

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Background Pain during topical aminolevulinic acid (ALA) mediated photodynamic therapy (PDT) limits the use of this treatment of skin diseases. Objective To summarize the effectiveness of interventions to reduce ALA-PDT related pain, and to explore factors contributing to pain induction. Methods A PubMed search was performed to identify all clinical PDT trials (2000–2008) that used ALA or methyl-ALA, enrolled at least 10 patients per trial, and used a semiquantitative pain scale. Results 43 papers were identified for review. Pain intensity is associated with lesion size and location and can be severe for certain diagnoses, such as plaque-type psoriasis. Results are inconsistent for the correlation of pain with light source, wavelength of light, fluence rate, and total light dose. Cooling represents the best topical intervention. Limitations Pain perception differs widely between patients and can contribute to variability in the reported results. Conclusion GABA receptors, cold/ menthol receptors (TRPM8), and vanilloid/capsaicin receptors (TRPV1) may be involved in pain perception during ALA-PDT and are therefore worthy of further investigation.

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Comparative benefit of two thermal spring waters after photodynamic therapy procedure

Abstract: This comparative clinical trial demonstrates that ATSW, a low mineral content spring water, can be useful after ALA-PDT in reducing postprocedure cutaneous inflammation and patient discomfort better than a high mineral content spring water.

Cited by 31 publications

References 15 publications

Beneficial effects of spraying low mineral content thermal spring water after fractional photothermolysis in patients with dermal melasma

Beneficial effects of spraying low mineral content thermal spring water after fractional photothermolysis in patients with dermal melasma

Effects of thermal water on skin regeneration

Pain associated with aminolevulinic acid-photodynamic therapy of skin disease

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