2010
DOI: 10.2147/dddt.s15133
|View full text |Cite
|
Sign up to set email alerts
|

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets

Abstract: BackgroundTramadol hydrochloride is available as 50 mg immediate-release (IR) and 100 mg, 200 mg, and 300 mg sustained-release (SR) tablets. The recommended dose of tramadol is 50–100 mg IR tablets every 4–6 hours. The tramadol SR 200 mg tablet is a better therapeutic option, with a reduced frequency of dosing, and improved patient compliance and quality of life. The present study evaluated the bioequivalence of a generic tramadol SR 200 mg tablet.MethodsA comparative in vitro dissolution study was performed o… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2014
2014
2022
2022

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 8 publications
(1 citation statement)
references
References 1 publication
0
1
0
Order By: Relevance
“…As the bioequivalence studies [21][22][23][24][25][26] are predominantly conducted in healthy volunteers, the candidate desiring to be a volunteer must be healthy in all aspects. He must fit the age criteria required for the study along with having the necessary BMI.…”
Section: Inclusion Criteria For Registrationmentioning
confidence: 99%
“…As the bioequivalence studies [21][22][23][24][25][26] are predominantly conducted in healthy volunteers, the candidate desiring to be a volunteer must be healthy in all aspects. He must fit the age criteria required for the study along with having the necessary BMI.…”
Section: Inclusion Criteria For Registrationmentioning
confidence: 99%