Comparative clinical efficacy of three toothpastes in the control of supragingival calculus formation

Kraivaphan, Petcharat; Amornchat, Cholticha

doi:10.4103/ejd.ejd_279_16

Cited by 11 publications

(10 citation statements)

References 14 publications

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“…5 Different components or supplements associated with fluoride were added as ingredients in these products aiming to reproduce the natural process of dental tissue mineralization 5,6 and boost the remineralization and regeneration potential of the hydroxyapatite. 7,8 Several promising biomimetic approaches to prevent tooth erosion have been investigated. One of the approaches comprises altering the dissolution properties of the hydroxyapatite with different foreign ions as substituents in the different sites of the hydroxyapatite molecule.…”

Section: Introductionmentioning

confidence: 99%

Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds

et al. 2021

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Objectives This in vitro study aimed to characterize the superficial and subsurface morphology of dental enamel treated with fluoridated gels containing different biomimetic compounds after erosive challenge. Materials and Methods Bovine incisor teeth were sectioned to obtain enamel blocks (4 mm × 4 mm × 6 mm; n = 5) that were demineralized to create an artificial caries lesion and treated by pH cycling interspersed with exposure to fluoridated toothpaste slurries under agitation. During pH cycling (demineralization and remineralization for 2 and 22 hours, respectively) for 6 days, the enamel blocks were exposed to toothpaste slurries under agitation with one of the dental gels: Regenerate Enamel Science (NR-5 technology), Daily Regenerator Dental Clean (REFIX technology), and Sensodyne Repair & Protect (Novamin technology). The enamel blocks were subjected to an erosive challenge, immersed in 50% citric acid for 2 minutes, and then washed with plenty of distilled water. The surface and cross-sectional micromorphology were assessed using scanning electron microscope (SEM). The elemental analyses (weight percentage) were determined with an energy-dispersive X-ray spectroscopy (EDS). Results Enamel treated with the product containing REFIX technology presented a smoother surface morphology compared to the other treatments. The higher resistance to the erosive challenge can be attributed to a silicon-enriched mineral layer formed on the enamel induced by the REFIX-based toothpaste. This was not observed in the specimens treated with the other technology-containing toothpastes. Conclusion The REFIX technology seemed to be the most promising compared to the Novamin and NR-5 technologies. In addition to forming a surface mineralized layer, the enamel treated with REFIX technology associated with the pH cycling resisted a subsequent erosive challenge.

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Section: Introductionmentioning

confidence: 99%

Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds

et al. 2021

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“…3,4 In this manner, several commercially available oral care products, containing different active ingredients associated with fluoride, claim to boost the remineralization and regeneration potential of these formulations. 5,6 The remineralization process can be enhanced by the substitution of small levels of ionic species in the different sites of the hydroxyapatite molecule. 7 Each ionic grouping of the hydroxyapatite molecule can be replaced by another ionic group of the same or different valence.…”

Section: Introductionmentioning

confidence: 99%

“… 3 4 In this manner, several commercially available oral care products, containing different active ingredients associated with fluoride, claim to boost the remineralization and regeneration potential of these formulations. 5 6 …”

Section: Introductionmentioning

confidence: 99%

Biomimetic Mechanism of Action of Fluoridated Toothpaste Containing Proprietary REFIX Technology on the Remineralization and Repair of Demineralized Dental Tissues: An In Vitro Study

Vilhena¹,

Oliveira

Matochek

et al. 2020

Eur J Dent

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Objectives This in vitro study aimed to characterize the mineral content and surface and cross-sectional morphology of enamel and dentin tissues treated with a 1450 ppm fluoride-containing toothpaste with REFIX technology. Materials and Methods Bovine enamel blocks (n = 5) were obtained (4 × 4 × 6 mm), demineralized (artificial caries lesion), and treated (pH cycling and brushing with the toothpaste). During the pH cycling, which lasted for 7 days (demineralization and remineralization took 6 and 18 hours, respectively), the enamel was brushed for 5 minutes using an electric toothbrush before being immersed in a remineralizing solution. The dentin blocks were acid-etched for 2 minutes (0.05 M citric acid, pH 1.8) to expose the dentinal tubules (n = 5). Morphological analysis of the dentin was performed immediately and after 7 days of brushing with the dentifrice, and compared with the control group. The specimens were then cross-sectioned. The surface and cross-sectional micromorphology were assessed using scanning electron microscopy (SEM). The elemental analyses (weight%) were determined with an energy-dispersive X-ray spectroscopy (EDS). Results The toothpaste with REFIX technology remineralized and repaired the surface enamel effectively. The elemental analysis also demonstrated that treating the enamel with the toothpaste formed a silicon-enriched mineral layer on the enamel surface. Elemental analysis of the enamel cross-sections showed that the toothpaste induced a mineral change. The results were also consistent in the dentin, where the dentinal tubules were progressively occluded until there was complete occlusion after 7 days. Conclusions We prove the biomimetic mechanism of action of fluoridated toothpaste containing proprietary REFIX technology for obtaining silicon-enriched, remineralized and repaired dental tissues.

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“…It must be pointed out that herbal agents can also be used in a dentifrice or mouth rinse vehicle, aiming to control supragingival plaque and gingivitis. Aloe vera, Abhaibhubejhr and miswak extract are some of the phytotherapics used in dentifrice form, while Anacardium occidentale and Ocimum sanctum are some of the plants that has been used in a mouth rinse formulation. Herbal products for gingivitis control tend to have fewer side effects and are generally cheaper than synthetic products.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of local phytotherapy in the nonsurgical treatment of periodontal disease: A systematic review

Moro

Souto

Franco

et al. 2018

J of Periodontal Research

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Herbal drugs are commonly used in the treatment of several diseases, including periodontitis. So far, no systematic review had evaluated the evidence regarding the efficacy of these agents in the treatment of periodontal disease. Therefore, the purpose of this review was to evaluate the effect of local application of phytotherapic agents as adjuncts to scaling and root planing (SRP), compared to SRP alone, on clinical parameters of chronic periodontal patients. Only randomized controlled trials of at least 3 months follow-up, of SRP alone in association with local phytotherapic agents were included. MEDLINE (PubMed), Google Scholar and LILACS databases were searched for articles published up to October 2016. Random-effects meta-analyses were conducted for clinical attachment level and probing pocket depth (PPD) change after treatment. Of 1861 papers potentially relevant, 7 were included. All studies showed that periodontal treatment in association with local phytotherapic delivery promotes a significant PPD reduction and the majority of them showed clinical attachment level gain. The local use of phytotherapy as an adjunct to SRP may promote additional benefits in PPD reduction and clinical attachment level gain. However, these results must be interpreted with caution due to the small sample size, high risk of bias and heterogeneity of the studies.

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Comparative clinical efficacy of three toothpastes in the control of supragingival calculus formation

Cited by 11 publications

References 14 publications

Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds

Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds

Biomimetic Mechanism of Action of Fluoridated Toothpaste Containing Proprietary REFIX Technology on the Remineralization and Repair of Demineralized Dental Tissues: An In Vitro Study

Efficacy of local phytotherapy in the nonsurgical treatment of periodontal disease: A systematic review

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