“…Regarding assessment characteristics, all the included studies (100%) assessed endothelial function (38-58) and seven (33%) also measured vascular smooth muscle function (40,41,43,(46)(47)(48)57). Fourteen studies (67%) measured endothelial function in the brachial artery (38-42, 44, 47-49, 53, 55-58), four (19%) in the radial artery (45,46,51,54), one (5%) in the femoral artery (52), and two (9%) in the brachial artery and lower limb arteries (i.e., femoral and posterior tibial) (43,50). Eleven studies (52%) placed the cuff distal to the appraised artery (38, 40-44, 46, 47, 49, 53, 56), ve (24%) proximal (45,51,54,55,58), and one (5%) positioned the cuff distal to the brachial artery and proximal to the posterior tibial artery (50), while four (19%) did not speci cally disclose this information (39, 48, 52, 57) and guidelines for measuring FMD were referenced (14,59).…”