1975
DOI: 10.1128/aac.7.2.179
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Comparative Effects of Amoxycillin and Ampicillin in the Treatment of Experimental Mouse Infections

Abstract: Amoxycillin was significantly more active than ampicillin in the treatment of intraperitoneal mouse infections when administered by oral and parenteral routes, although the causal bacteria were equally susceptible in vitro to the two penicillins. Amoxycillin produced higher antibiotic blood concentrations in mice than ampicillin after oral administration, and this was a possible explanation for the superior oral activity of amoxycillin. In contrast, antibiotic blood concentrations were the same for both compou… Show more

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Cited by 41 publications
(1 citation statement)
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“…Addition of ampicillin blocks cell division and made cells elongated (Fig. 4) which matches with the previous result (Comber et al, 1975). However, the addition of indole (1 mM) in the presence and absence of ampicillin does not affect cell morphology.…”
Section: Resultssupporting
confidence: 91%
“…Addition of ampicillin blocks cell division and made cells elongated (Fig. 4) which matches with the previous result (Comber et al, 1975). However, the addition of indole (1 mM) in the presence and absence of ampicillin does not affect cell morphology.…”
Section: Resultssupporting
confidence: 91%