Comparative Effects of Sodium Selenite and Selenomethionine upon Nutritional Muscular Dystrophy, Selenium-Dependent Glutathione Peroxidase, and Tissue Selenium Concentrations of Turkey Poults

Cantor, A. H.; Moorhead, P. D.; Musser, Margery A.

doi:10.3382/ps.0610478

Cited by 75 publications

(50 citation statements)

References 17 publications

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“…It was probably caused by differences in metabolic pathways (Forstrom et al, 1978). The observed differences in GSH-Px activity in our study are in agreement with results published by other authors (Cantor et al, 1982;Hassan et al, 1988;Spears et al, 2003;Dlouhá et al, 2008), who found that selenium supplementation increased GSH-Px activity. In addition, GSH-Px activity was significantly higher in the case of using SS in comparison with SCH.…”

Section: Discussionsupporting

confidence: 83%

“…Inconsistent results were also obtained for selenium deposition in poultry meat after SS addition. Our results correspond with the findings of some authors (Cantor et al, 1982;Payne and Southern, 2005;Ševčíková et al, 2006;Dlouhá et al, 2008;Skřivan et al, 2008a,b), who showed an increase in selenium in the breast meat of poultry fed selenomethionine, SCH and selenium-enriched yeast. The published results are ambiguous in the case of SS.…”

Section: Discussionsupporting

confidence: 82%

“…Shan and Davis (1994) reported an increase in selenium concentration in the breast meat of chickens that received SS. Whereas, Cantor et al (1982), Payne and Southern (2005) or Dlouhá et al (2008) ascertained no significant differences in breast muscle selenium content after SS addition. In our study, selenium content in breast meat increased after SS addition, but no significant differences were found between the levels.…”

Section: Discussionmentioning

confidence: 93%

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The effect of dietary selenium sources and levels on performance, selenium content in muscle and glutathione peroxidase activity in broiler chickens

Heindl¹,

Ledvinka²,

Englmaierová³

et al. 2010

Czech J. Anim. Sci.

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The study examined the effect of dietary supplements of sodium selenite (SS), selenium-enriched yeast (Sel-Plex®, SP) and selenium-enriched alga Chlorella (SCH) on growth traits, carcass analysis, selenium content in breast meat, glutathione peroxidase (GSH-Px) activity in breast and thigh meat and liver of chickens. The experiment was realized with seven hundred thirty-five cockerels Ross 308 randomly divided into 7 dietary treatments with 3 replications in each treatment. Chickens were fed a diet supplemented with 0 (control), 0.15 or 0.30 mg of selenium/kg in the form of sodium selenite (SS), Sel-Plex® (SP) and selenium-enriched alga Chlorella (SCH). Selenium addition influenced body weight at 21 (P ≤ 0.001) and 35 (P ≤ 0.05) days of age. Significantly higher body weight at 35 days of age was determined in chickens receiving 0.15 mg of selenium from SP (2 122 g) and 0.3 mg of selenium from SCH (2 116 g) contrary to dietary treatment with a lower level of selenium from SCH (2 010 g) per kg of feed. The selenium content in breast muscle was increased (P ≤ 0.001) by both the lower and higher selenium concentration in the form of SP (0.6 and 0.85 mg/kg dry matter) and SCH (0.6 and 0.82 mg/kg dry matter) in comparison with the control (0.31 mg/kg dry matter). A significant increase (P ≤ 0.001) was ascertained even in SS treatments, but no significant differences were found between both levels. The selenium source and level, including SS, significantly (P ≤ 0.001) influenced the GSH-Px activity in breast and thigh meat.  

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 93%

See 1 more Smart Citation

The effect of dietary selenium sources and levels on performance, selenium content in muscle and glutathione peroxidase activity in broiler chickens

Heindl¹,

Ledvinka²,

Englmaierová³

et al. 2010

Czech J. Anim. Sci.

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“…In the present study, GSH-Px activity in serum and in the studied organs was greatly improved by dietary Se supplementation while the SS group had similar GSH-Px activity in serum, liver and kidney like the Se-Met group but higher in pancreas and breast muscle than the Se-Met group. These results were consistent with earlier reports of Cantor et al (1975Cantor et al ( , 1982 and Payne and Southern (2005b). Less pronounced increases in GSH-Px activity by supplementation of Se-Met compared to SS are probably due to the fact that Se, regardless of its form, must be converted to Se-Cys before it can be incorporated into the selenoprotein enzyme GSH-Px (Forstrom et al, 1978).…”

Section: Discussionsupporting

confidence: 83%

Effects of selenomethionine and sodium selenite supplementation on meat quality, selenium distribution and antioxidant status in broilers

Wang¹,

Zhan²,

Yuan³

et al. 2011

CZECH J ANIM SCI

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This study was conducted to investigate the effects of selenomethionine (Se-Met) and sodium selenite (SS) supplementation on meat quality, selenium (Se) distribution, and antioxidant status in broilers. A total of 360 seven-days-old Ross 308 broilers of an average body weight 162 ± 0.59 g were randomly allotted to three treatments, each of which included three replications of 40 birds. The treatments included a control diet containing 0.04 mg Se/kg and other two diets that contained 0.15 mg Se/kg supplemented by SS or Se-Met. The experiment lasted for 42 days. Selenium supplementation improved (P < 0.05) the Hunter a value of breast muscle in 8 and 16 h and decreased (P < 0.05) the drip loss of breast muscle in 24 and 48 h. Both Se sources and exposed time significantly influenced (P < 0.01) the drip loss of breast muscle. Selenium and glutathione concentrations in serum and in the studied organs were significantly higher (P < 0.05) after dietary Se supplementation while the Se-Met group showed the highest value (P < 0.05). Glutathione peroxidase activity in serum and in the studied organs was also significantly elevated (P < 0.05) by dietary Se supplementation while SS increased the glutathione peroxidase activities in pancreas and breast muscle to a larger extent (P < 0.05) than did Se-Met. The addition of Se from either source caused a significant increase (P < 0.05) in superoxide dismutase activities in tissues (except for kidney) whereas the Se-Met group was more effective (P < 0.05) than the SS group in breast muscle. Selenium supplementation increased (P < 0.05) the total antioxidant capability in serum, liver, kidney and breast muscle while the Se-Met group proved to be more effective (P < 0.05) than the SS group except for kidney. The Se-supplemented diets had a lower (P < 0.05) malondialdehyde concentration in serum and in the studied organs but the effect was more pronounced (P < 0.05) when Se-Met was used except for the serum. These results indicated that Se-Met supplementation was more effective than SS supplementation for depositing Se in serum and tissues, enhancing the antioxidant status and reducing the drip loss of breast muscle.

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“…In chickens, Cantor et al (8) reproduced muscular dystrophy through Se-deficient diet with normal vitamin E content. The chickens were hatched from the eggs of breeders, which also received a ration deficient in selenium.…”

Section: Introductionmentioning

confidence: 99%

Reproduction of muscular dystrophy in broiler chickens through early nutrition with deficient feed supplemented with oxidised fat

Stoyanchev¹,

Maruzova²

2017

TJS

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The purpose of the present study was the experimental reproduction of muscular dystrophy in broiler chickens through early nutrition with a diet deficient in vitamin E, selenium and sulfur-containing amino acids, supplemented with oxidised fat in order to throw light on the etiopathogenesis, clinical signs, diagnosis, course, treatment and prognosis of the disorder. The experiments were conducted with 1 dayold Cobb 500 broiler chickens. By the 3 rd day of life, they were divided into 60 experimental and 20 control birds; the latter were fed a standard compound feed whereas the former group received a diet deficient in sulfur-containing amino acids methionine and cysteine (reduced up to 50%), vitamin E, and Se (from 0.2 mg/kg in standard feed to 0.01 mg/kg), further supplemented with 4% oxidized fat containing peroxides and aldehydes with peroxide number of the food 8.0 meq O 2 /kg. Peroxide number (meq O 2 /kg) was determined in pork lard oxidised through UV irradiation as per BSS 11374:1986. The clinical signs of experimental muscle dystrophy in broiler chickens appeared first by the 19 th day of feeding, when the severe clinical form was established and by the 21 st and 25 th day in the severe and the mild clinical form. The proportion of diseased chickens during the clinical period was the highest (93.3% mild and 46.6% severe clinical form), and gradually decreased after the treatment with Seled ® . The 7-day treatment with Seled ® at a dose of 0.06 mg/kg per os for compensation of Se deficiency and replacement of the deficient compound feed with a regular one contributed to recovery of birds by the 31 st day after the therapy of mild experimental muscular dystrophy while birds affected by the severe clinical form could not recovery.

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Comparative Effects of Sodium Selenite and Selenomethionine upon Nutritional Muscular Dystrophy, Selenium-Dependent Glutathione Peroxidase, and Tissue Selenium Concentrations of Turkey Poults

Cited by 75 publications

References 17 publications

The effect of dietary selenium sources and levels on performance, selenium content in muscle and glutathione peroxidase activity in broiler chickens

The effect of dietary selenium sources and levels on performance, selenium content in muscle and glutathione peroxidase activity in broiler chickens

Effects of selenomethionine and sodium selenite supplementation on meat quality, selenium distribution and antioxidant status in broilers

Reproduction of muscular dystrophy in broiler chickens through early nutrition with deficient feed supplemented with oxidised fat

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