2015
DOI: 10.14260/jemds/2015/1730
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Comparative Efficacy and Safety of Olmesartan Versus Losartan in Patients With Hypertension

Abstract: Angiotensin II receptor blockers (ARBs) are the newest class of approved antihypertensive agents and the second class of drugs to exert their primary antihypertensive action by interrupting the renin-angiotensin system. It was a multicenter, randomized, double-blind trial in which efficacy of Olmesartan (20mg once a day) and losartan (50mg once a day) was compared in patients with hypertension. In patients with a cuff diastolic blood pressure (DBP) of ≥100 and ≥115 mm Hg and a mean daytime DBP of ≥90mm Hg and … Show more

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“…These results demonstrated a greater effectiveness of olmesartan in decrease BP when compared with losartan, reaching basically the same values as for the WKY healthy group. These findings are in line with the results of previous works …”
Section: Resultssupporting
confidence: 94%
“…These results demonstrated a greater effectiveness of olmesartan in decrease BP when compared with losartan, reaching basically the same values as for the WKY healthy group. These findings are in line with the results of previous works …”
Section: Resultssupporting
confidence: 94%