Comparative efficacy of the Antiplaque Effect of Natural Honey Mouthwash and Chlorhexidine Mouthwash. A randomized controlled trial

Abstract

Objectives: To compare the efficacy of natural Honey (10%) and chlorhexidine mouthwash (0.12%) on the dental plaque levels. Moreover, to evaluate the efficacy of natural Honey and chlorhexidine mouthwash on the level of dental plaque.
 Methods: This study was a single-centered randomized controlled trial conducted on participants attending the Dental OPD of Dar-ul-Sehat hospital in Karachi. A total of 60 participants were included in the trial from June 2020 to December 2020. The sample size was calculated using openepi after entering the mean and SD of the honey and chlorhexidine groups. The study included sixty male and female participants ranging in age from 18 to 25 years, and those with medical illness, missing teeth, and antimicrobial history were excluded from the study. The subjects were randomly assigned to two groups: Natural Honey or Chlorhexidine gluconate mouthwash. The data was collected at the baseline and 14th day; the plaque was revealed using a disclosing solution. Their scores were recorded at four sites per tooth using the Silness-Loe plaque index criteria. Later, statistical analysis was performed to compare the effects of the two groups. P ? 0.05 was considered statistically significant.
 Results: Our findings revealed that both groups effectively lowered the plaque score. However, it showed a more significant reduction in plaque indices in the honey group on Day 14 when compared to chlorhexidine mouthwash.
 Conclusion: Honey has been identified as a potent antibacterial agent with therapeutic properties. Based on the findings of this study, it is possible to conclude that gargling with the original honey 10% solution is effective in lowering dental plaque score. Honey can be used in relation to conventional treatments to protect dental plaque and gingivitis. More research will be needed to back up these preliminary findings. Moreover, the synergistic effect of Chlorhexidine with natural Honey must be investigated

The potential of rambutan honey toothpaste in reducing the dental plaque index: a quasi Experimental study

“…The results of this study are supported by research conducted by Sruthi, et al in 2021 which states that honey mouthwash can reduce the plaque index and gingivitis index. 15 A similar study was also conducted by Abid, et al in 2022 stated that honey mouthwash is more effective in reducing plaque compared to chlorhexidine mouthwash which is the gold standard. This decrease in plaque occurs because the antibacterial activity of honey can affect the attachment of Streptococcus mutans bacteria to the tooth surface which is the initial stage of dental plaque formation.…”

“…This decrease in plaque occurs because the antibacterial activity of honey can affect the attachment of Streptococcus mutans bacteria to the tooth surface which is the initial stage of dental plaque formation. 9,15 Factors that contribute to the antibacterial activity of rambutan honey are high sugar content and low water content, pH/acidity level, Methylglyoxal (MGO), organic compounds contained in honey such as flavonoids, polyphenols and glycosides, and H2O2 (hydrogen peroxide). 9 The water content in honey ranges from 0.562 to 0.62, this low enough water content allows the disruption of the growth of bacteria or other microorganisms.…”