Comparative Evaluation of Chlorhexidine and its Combination with Chitosan as Intracanal Medicaments on Enterococcus faecalis in Endodontic Retreatment

Abstract

in vivo evaluation of synergistic effect of chitosan and its combination with CHX as intracanal medicament against the resistant bacteria like E,faecalis will have important clinical implications in nonsurgical endodontiv retreatment. Hence, the aim of this clinical study is to evaluate the antimicrobial efficacy of chlorhexidine and its combination with chitosan as intracanal medicament in response to E. faecalis in retreatment cases. Materials and Methods Thirty patients between 19-65 years of age requiring root canal retreatment were selected for the study. All selected teeth were single rooted which were symptomatic or asymptomatic and had history of root canal treatment and showed periapical radiolucency upto 4mm. Ethical clearance was obtained from the institutional ethical committee. All patients were explained about the treatment procedure and informed consent was taken. The selected tooth was isolated with a rubber dam. The crown and surrounding rubber dam were disinfected with 30% hydrogen peroxide for 30s followed by vigorous swabbing of 3% sodium hypochlorite solution. Subsequently 5% sodium thiosulfate was used to inactivate the disinfectant. Access preparation was done with a sterile Endo access

Assessment of Antimicrobial Efficacy of Nano Chitosan, Chlorhexidine, Chlorhexidine/Nano Chitosan Combination versus Sodium Hypochlorite Irrigation in Patients with Necrotic Mandibular Premolars: A Randomized Clinical Trial

“…Bacteria play an essential role in pathogenesis of apical periodontitis; therefore, success of root canal treatment depends on its eradication before root canal obturation [1]. Bacteria remaining within the root canal system after obturation can contribute to endodontic failures [2]. Different studies that used modern techniques such as micro computed tomography scanning to assess the effects of instrumentation on root canals after using different techniques have concluded that proportionally great parts of the root canal walls remained unprepared by the endodontic instruments enhancing the value of chemical preparation [3].…”