Comparative Evaluation of Different Techniques for Aflatoxin Detoxification in Poultry Feed and Its Effect on Broiler Performance

Mahmood, Tariq; Pasha, T. N.; Khattak, Farina

doi:10.5772/22134

Cited by 4 publications

(1 citation statement)

References 60 publications

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“…• Mahmood et al (2011) reviewed the comparative evaluation of different techniques for AF detoxification in poultry feed and its effect on broiler performance, with 93 related references.…”

Section: Pakistanmentioning

confidence: 99%

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Oguz¹

2016

EurasianJVetSci

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Section: Pakistanmentioning

confidence: 99%

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Oguz¹

2016

EurasianJVetSci

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Role of clay in detoxification of aflatoxin B1 in growing Japanese quail with reference to gender

Mahrose

Michalak

Farghly³

et al. 2021

Vet Res Commun

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Ameliorative effect of nanocurcumin and Saccharomyces cell wall alone and in combination against aflatoxicosis in broilers

et al. 2022

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Background The adverse effect of aflatoxin in broilers is well known. However, dietary supplementation of Saccharomyces cell wall and/or Nanocurcumin may decrease the negative effect of aflatoxin B1 because of the bio-adsorbing feature of the functional ingredients in Yeast Cell Wall and the detoxification effect of curcumin nanoparticles. The goal of this study was to see how Saccharomyces cell wall/Nanocurcumin alone or in combination with the aflatoxin-contaminated diet ameliorated the toxic effects of aflatoxin B1 on broiler development, blood and serum parameters, carcass traits, histology, immune histochemistry, liver gene expression, and aflatoxin residue in the liver and muscle tissue of broilers for 35 days. Moreover, the withdrawal time of aflatoxin was measured after feeding the aflatoxicated group an aflatoxin-free diet. Broiler chicks one day old were distributed into five groups according to Saccharomyces cell wall and/or nanocurcumin with aflatoxin supplementation. The G1 group was given a formulated diet without any supplements. The G2 group was supplemented with aflatoxin (0.25 mg/kg diet) in the formulated diet. The G3 group was supplemented with aflatoxin (0.25 mg/kg diet) and Saccharomyces cell wall (1 kg/ton diet) in the formulated diet. The G4 group was supplemented with aflatoxin (0.25 mg/kg diet) and nanocurcumin (400 mg/kg) in the formulated diet. The G5 group was supplemented with aflatoxin (0.25 mg/kg diet) and Saccharomyces cell wall (1 kg/ton diet) in combination with nanocurcumin (200 mg/kg) in the formulated diet. Results According to the results of this study, aflatoxin supplementation had a detrimental impact on the growth performance, blood and serum parameters, carcass traits, and aflatoxin residue in the liver and muscle tissue of broilers. In addition, aflatoxin supplementation led to a liver injury that was indicated by serum biochemistry and pathological lesions in the liver tissue. Moreover, the shortening of villi length in aflatoxicated birds resulted in a decrease in both the crypt depth ratio and the villi length ratio. The expression of CYP1A1 and Nrf2 genes in the liver tissue increased and decreased, respectively, in the aflatoxicated group. In addition, the aflatoxin residue was significantly (P ≤ 0.05) decreased in the liver tissue of the aflatoxicated group after 2 weeks from the end of the experiment. Conclusion Saccharomyces cell wall alone or with nanocurcumin attenuated these negative effects and anomalies and improved all of the above-mentioned metrics.

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Comparative Evaluation of Different Techniques for Aflatoxin Detoxification in Poultry Feed and Its Effect on Broiler Performance

Cited by 4 publications

References 60 publications

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Role of clay in detoxification of aflatoxin B1 in growing Japanese quail with reference to gender

Ameliorative effect of nanocurcumin and Saccharomyces cell wall alone and in combination against aflatoxicosis in broilers

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