Comparative Evaluation of Newer Remineralizing Agents on Surface Characteristics of Tooth Surface After Slenderization: An In Vitro Study

Abstract

Aim: The aim of the present study was to compare the effects of remineralizing agents (nano-hydroxyapatite [n-HAP], NovaMin, calcium sucrose phosphate [CaSP], and Pro-Argin) on surface characteristics of slenderized enamel using Vickers microhardness and scanning electron microscope–energy dispersive X-ray (SEM-EDX) analysis. Materials and Method: Sixty extracted premolar teeth were divided into 6 groups: group 1—natural teeth; group 2—slenderization and polishing; group 3—n-HAP; group 4—NovaMin; group 5—CaSP; and group 6—Pro-Argin. Remineralizing agents were applied for 21 days. Specimens were evaluated using Vickers microhardness and SEM-EDX analysis. A 1-way analysis of variance (ANOVA) and post-hoc Tukey honestly significant difference (HSD) test were used for intragroup comparisons. Results: Among all remineralizing agents, CaSP showed significantly maximum surface microhardness, followed by NovaMin, n-HAP, and Pro-Argin. SEM also showed increased surface roughness for all remineralizing agents. EDX showed maximum increase in mineral content obtained with CaSP. Conclusion: All remineralizing agents significantly remineralized the stripped enamel surface. CaSP demonstrated promising results by effectively and significantly remineralizing the enamel lesions as compared to other test agents.

Effectiveness of different toothpastes in treating white spot lesions: A laboratory study

“…The findings of the present study are in alignment with the outcomes of Yu et al [41] and Nanwal et al [42]. Both studies highlighted that the combination of 8% arginine and fluoride within a calcium carbonate base yields enhanced re-mineralization effects.…”

“…Both studies highlighted that the combination of 8% arginine and fluoride within a calcium carbonate base yields enhanced re-mineralization effects. Nanwal et al [42] conducted an investigation on the impact of various agents, including n-HAp particles, NovaMin, Pro-Argin, and calcium sucrose phosphate, on the process of remineralization. EDX analysis revealed that all tested re-mineralizing agents effectively restored the mineral content lost due to inter-proximal stripping.…”

Comparative Evaluation of Dental Enamel Microhardness Following Various Methods of Interproximal Reduction: A Vickers Hardness Tester Investigation

“…While these methods ensure efficient grinding with high yield in terms of creating the necessary space for correcting dental crowding, they leave behind increased roughness unsuitable for tooth health and reduced hardness [45]. The use of 15 µm abrasive strips and polishing abrasive discs in the stripping procedure safely removes dental enamel, achieving a surface similar to that of intact enamel and very good microhardness values [10,37,45,47,49,52].…”

“…Additionally, enamel microhardness is closely related to its inorganic phospho-calcium component and the ongoing process of enamel remineralization in the oral cavity. As the remineralization of an enamel surface in the oral cavity is a complex process, the limitations of this in vitro study include the difficulty of precisely simulating biological aspects; artificial saliva is composed only of inorganic ions, and the effects of salivary proteins, pellicle, and plaque on mineralization inhibition have not been considered [52]. Other confounding factors involve the possibility of experimental errors and differences in the enamel's microstructure between samples.…”