Comparative Evaluation of Phototherapeutic Keratectomy and Amniotic Membrane Transplantation for Management of Symptomatic Chronic Bullous Keratopathy

Abstract

Both PTK and AMT are comparable in providing symptomatic relief in patients with bullous keratopathy and poor visual potential.

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

“…Topical corticosteroids and nonsteroidal medications appear to have no benefit in dogs . In human patients, treatment options include therapeutic soft contact lenses, anterior stromal puncture with or without neodymium: yttrium–aluminum–garnet laser, phototherapeutic keratectomy, conjunctival flaps, and amniotic membrane transplantation . In dogs, thermokeratoplasty and conjunctival flaps have been proposed for the treatment of BK.…”

Corneal Edema and Opacification Preferred Practice Pattern®

“…Table 2 lists many of the more common keratectomy and keratoplasty procedures. or greater has been used alone [48][49][50] or in combination with self-retaining amniotic membrane grafts 51,52 to reduce pain and promote surface stability. Pain relief is purportedly achieved by ablation of the sub-basal nerve plexis.…”

Phototherapeutic keratectomy

“…The surgical procedure is most commonly performed for elevated corneal lesions, anterior corneal dystrophies, and recurrent corneal erosions (RCEs). 16 Other less common indications include symptomatic bullous keratopathy, 30,111,198,210 primary and recurrent pterygium, 146,197,212 band keratopathy, 69,132,188 post-laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) complications, 13,100,104,170,187 recurrent intraepithelial corneo-conjunctival carcinoma, 181 and dye migration after corneal tattooing. 36…”

“…Various other studies also report significant symptomatic improvement after PTK, which is the primary goal of the treatment (Table 1). 30,102,111,198,210 7.1.5. Band keratopathy PTK has been shown to be an effective surgical procedure for stabilization of the ocular surface, in the eyes with band keratopathy.…”