Comparative Evaluation of Preoperative Short Course Radiotherapy Versus Long Course Chemoradiotherapy for the Treatment of Rectal Cancer

Abstract

family history, inflammatory bowel disease, obesity, processed meat, refined diet, alcohol consumption and smoking are the genetic or enviromental factors of developing colorectal cancer.Management of rectal cancer is considered with surgery as a primary treatment while local recurrence rates vary between 20-50 percent. So dramatic changes were released in recent 20 years. Depth of penetration and regional node involvement are the associated factors for recurrence. Neoadjuvant therapy including chemoradiotherapy, hypofractionated radiotherapy or chemotherapy plus surgery results with better outcomes