Comparative evaluation of the platelet-rich fibrin bandage versus gelatin sponge-assisted palatal wound healing of free gingival graft donor site: A case series

Abstract

Periodontal plastic surgery often involves palatal donor site, thereby creating an open wound that is prone to postoperative complications such as bleeding, pain, and slow healing process. To prevent the same, platelet-rich fibrin (PRF) and gelatin sponge (GS) were utilized equally at the donor site in six patients. Patients were monitored at the 1st, 2nd, 3rd, and 4th weeks after surgery for postoperative discomfort (D), consumption of analgesics during first postoperative week, alteration of sensitivity (AS), change in feeding habits (CFH), complete wound epithelialization (CWE), and healing index (Landry et al. 1998). Two patients in the GS group showed significantly early CWE, higher healing index score, and less D, AS, and CFH postoperatively in comparison to the PRF group. It was suggested that GS can also be considered as an effective, economical, and biocompatible dressing material of choice to enhance wound healing and to minimize postoperative complications associated with the donor site.

Wound‐healing agents for palatal donor area: A network meta‐analysis

“…(2022) observed that collagen hemostatic sponge promoted better pain control when associated with hyaluronic acid gel than with periodontal dressing. In comparison to L‐PRF, lower pain levels were obtained for L‐PRF in comparison to collagen hemostatic sponge in three studies (Femminella et al., 2016; Hassan et al., 2020; Sousa et al., 2020), however, collagen hemostatic sponge promoted more less levels of pain in comparison to L‐PRF in one case series (Belkhede et al., 2019). Schinini et al.…”

“…Most of included studies evaluating palatal donor sites covered with L‐PRF membranes in comparison to spontaneous healing (Lektemur Alpan & Torumtay Cin, 2020; Reddy et al., 2015; Shakir et al., 2015), non‐eugenol pack (Aravindaksha et al., 2014; Bahammam, 2018; Kulkarni et al., 2014), collagen hemostatic sponge (Femminella et al., 2016; Hassan et al., 2020; Sharma et al., 2019), cyanoacrylate adhesive (Ozcan et al., 2017) and hyaluronic acid gel (Hassan et al., 2020) reported considerably faster healing with L‐PRF membranes. Only one case series (with 3 patients per group) showed superior results for collagen hemostatic sponge in comparison to L‐PRF (Belkhede et al., 2019) and one RCT showed no differences between both groups (Alvarez‐Medina et al., 2023). Two studies reported better healing with palatal donor sites treated with titanium‐prepared platelet‐rich fibrin (T‐PRF) in comparison to collagen hemostatic sponge (Koca‐Ünsal et al., 2022) and acrylic stent (Gülbahar Ustaoglu et al., 2016).…”

“…reported considerably faster healing with L-PRF membranes. Only one case series (with 3 patients per group) showed superior results for collagen hemostatic sponge in comparison to L-PRF(Belkhede et al, 2019) and one RCT showed no differences between both groups(Alvarez-Medina et al, 2023). Two studies reported better healing with palatal donor sites treated with titanium-prepared platelet-rich fibrin (T-PRF) in comparison to collagen hemostatic sponge (Koca-Ünsal et al, 2022) and acrylic stent (GülbaharUstaoglu et al, 2016).…”

Ultrasonographic evaluation of the titanium‐prepared platelet‐rich fibrin effect in free gingival graft procedures

“…There are many studies in the literature in which PRF or T‐PRF membrane application as palatal dressing after FGG harvesting; 15,32,35,43,47–49 however, those studies only evaluated the parameters clinically. In this study, the efficiency of T‐PRF application was evaluated radiologically for the first time.…”

Regeneración ósea con fibrina rica en plaquetas e injerto óseo autólogo post extracción de canino impactado. Reporte de caso

“…En la práctica clínica, un injerto óseo de tuberosidad maxilar a menudo se ha utilizado como un injerto particulado para el aumento alveolar deficiente o del seno maxilar antes o simultáneamente (11) . La Fibrina Rica en Plaquetas (FRP), es un material biocompatible autógeno y concentrado plaquetario de segunda generación (12) , contiene leucocitos, plaquetas y factores de crecimiento, indispensables para la cicatrización (13).…”