Comparative evaluation of three different toothpastes on remineralization potential of initial enamel lesions: A scanning electron microscopic study

Chandru, TP; Yahiya, M Bazanth; Peedikayil, Faizal C; Dhanesh, N.; Natarajan, Srikant; Kottayi, Soni

doi:10.4103/ijdr.ijdr_745_18

Cited by 12 publications

(10 citation statements)

References 3 publications

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“…A study conducted by Chandru et al [26] corroborates the current findings, as it also demonstrated that Colgate® Sensitive Plus toothpaste with Pro-Argin™ formula exhibited the highest re-mineralization effect on enamel blocks, followed by Biorepair toothpaste. Interestingly, there were no significant differences in enamel re-mineralization between Colgate® Sensitive Plus and Biorepair toothpastes on the 6 th , 9 th , and 12 th days of pH-cycling.…”

Section: Discussionsupporting

confidence: 89%

“…Their penetration into enamel pores created during the progression of caries and the subsequent filling of these empty spaces help achieving re-mineralization. As a result, they act as anchor points for further mineral deposition, leading to elevated mineral content [26].…”

Section: Discussionmentioning

confidence: 99%

“…Despite these variations in results, the reliability and safety of hydroxyapatite-based toothpaste, including zinc-carbonate formulations, continue to stand out for re-mineralization and caries prevention. Numerous studies findings not only position it on par with fluoride toothpaste, but also suggest its superiority, surpassing the performance of fluoride toothpaste [26,36].…”

Section: Discussionmentioning

confidence: 99%

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Effectiveness of different toothpastes in treating white spot lesions: A laboratory study

Fadhle,

Abd El Latief,

Hegazy

et al. 2024

jos

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Introduction: Strategy for managing caries has evolved into focusing on early detection of caries lesions and non-invasive treatment of initial lesions using innovative re-mineralizing agents. Objectives: Aim of the study was to compare the ability of commercially available toothpaste formulations containing zinc-carbonate nano-hydroxyapatite (ZnCO 3 /n-HAp), 8% arginine and calcium carbonate (Pro-Argin), and fluoride to promote re-mineralization in artificially induced white spot lesions. Material and methods: A total of thirty-six sound premolars were randomly allocated into four groups according to the assigned toothpaste: G1 -ZnCO 3 /n-HAp, G2 -Pro-Argin, G3 -positive control (fluoride toothpaste), G4 -negative control (artificial saliva). A scanning electron microscope (SEM) and energy dispersive X-ray (EDX) analyses were conducted at the baseline to assess calcium (Ca) and phosphorus (P) content. Following the induction of white spot lesions, a pH cycle was implemented involving a 7-day application of the toothpastes. Readings were taken both after de-mineralization and at subsequent re-mineralization phases. Collected data were subjected to statistical analysis using SPSS software version 25.0. Results: The highest mean difference in Ca/P ratio was observed in the G2 group, followed by the G1, G3, and G4 groups in descending order. There were statistically significant differences between all the experimental toothpaste groups (G1, G2, and G3) and the negative control group (G4). However, no statistically significant difference was found among the tested toothpaste groups. Conclusions: All three toothpastes tested were found to be effective in promoting re-mineralization of initial enamel lesions, with no evidence of superiority of one over the others.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Effectiveness of different toothpastes in treating white spot lesions: A laboratory study

Fadhle,

Abd El Latief,

Hegazy

et al. 2024

jos

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“…Afterward, the anatomical crowns of the teeth were mounted on acrylic resin (Acropars, Iran) so that only the enamel surfaces were exposed to apply materials in the next steps. The surface of the enamel was rubbed and smoothed using waterproof silicon carbide paper grit 1200 (Struers Company, Germany) in 10 back-and-forth movements to obtain a suitable surface for the microhardness test (16). A demineralizing solution containing 0.05 M lactic acid, 2.2 mM calcium chloride, and 2.2 mM sodium dihydrogen orthophosphate was made, and potassium hydroxide pellets were added to stabilize the pH of the solution at 4.5 (16).…”

Section: Methodsmentioning

confidence: 99%

“…This structure has sodium, potassium, magnesium, and calcium, which cause bone formation (15). Whole fish bone also contains calcium carbonate and pure hydroxyapatite, which makes it suitable for tissue engineering (16). Little evidence is available about the effect of NovaMin toothpaste on enamel lesions.…”

mentioning

confidence: 99%

Comparison of the Remineralization Effect of Nano Herbal Toothpaste With Two Kinds of Toothpaste Containing Fluoride and Bioactive Glass on Primary Enamel Lesions: An In Vitro Study

Asgartooran,

Shokripour,

Ayubi

et al. 2023

Avicenna J Dent Res

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Background: Considering the therapeutic properties of the compounds used in Albodent Iranian toothpaste and little evidence about the effect of NovaMin toothpaste on primary caries lesions, the purpose of this research was to compare the effect of toothpaste containing fluoride and toothpaste containing bioactive glass with Albodent toothpaste on enamel remineralization in a laboratory manner. Methods: Overall, 24 healthy human premolar teeth were selected and divided into buccal and lingual halves. The demineralization cycle of the samples was performed for 14 days. The samples were classified into four groups and were brushed twice a day for 28 days with tested toothpaste. A microhardness test was conducted, and changes in the enamel surface and morphology of one sample selected from each group were evaluated by scanning electron microscopy. The analysis of variance and Tukey’s tests were used for the statistical analysis of the data. Results: The average difference in microhardness in the studied groups was statistically significant (P<0.05) when compared two-by-two with the control group. The most noticeable difference was found in the comparison of the Sensodyne group with the control group, while the lowest difference was observed in the comparison of the Albodent group with the control group. Conclusion: The presence of NovaMin in toothpaste along with fluoride can increase the efficiency of the remineralization rate of primary enamel lesions compared to fluoride toothpaste without bioactive glass. In addition, the effectiveness of herbal toothpastes, which do not contain essential artificial ingredients in the remineralization of primary enamel lesions was lower than that of non-herbal fluoride toothpastes.

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Evaluation of caries remineralization potential of toothpastes containing three remineralizing agents - calcium sucrose phosphate, β tricalcium phosphate and fluoro calcium phosphosilicate: An in vitro study

PS,

Dinakaran,

et al. 2023

Int. J. Appl. Dent. Sci.

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The "Minimally invasive" approach for caries incorporates detecting carious lesions in the incipient stage and treating those lesions using remineralizing agents, thus emphasizing prevention rather than the traditional method. Aim: To evaluate the remineralizing potential of three different tooth remineralizing agents (Calcium Sucrose Phosphate, Functionalised β Tricalcium Phosphate and Fluoro Calcium Phosphosilicate) on demineralized tooth surfaces using Vickers microhardness test and Atomic Force Microscopy. Materials and Methods: Thirty freshly extracted mandibular premolars were collected. The prepared enamel samples were assigned to three different groups with ten specimens each. The specimens were then demineralized using McInne's demineralizing solution in two cycles. Remineralization was carried out for fifteen and thirty days in two cycles using Calcium Sucrose Phosphate (ENAFIX), Functionalised β Tricalcium Phosphate (Clinpro Tooth Crème), and Fluoro Calcium Phosphosilicate (ELSENZ) containing toothpastes for groups I, II, III respectively. The specimens were subjected to Vickers microhardness test and Atomic force microscopic evaluation post-demineralization and remineralization cycles. The results were tabulated and statistically analysed. Results: Study results showed that the three remineralizing agents tested increased Vicker's hardness number values and decreased the surface roughness significantly in a span of 30 days. Their remineralisation potential was effective. Conclusion: β TriCalcium Phosphate (Clinpro tooth crème) has superior remineralizing efficacy compared to the other two remineralizing toothpastes.

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Comparative evaluation of three different toothpastes on remineralization potential of initial enamel lesions: A scanning electron microscopic study

Cited by 12 publications

References 3 publications

Effectiveness of different toothpastes in treating white spot lesions: A laboratory study

Effectiveness of different toothpastes in treating white spot lesions: A laboratory study

Comparison of the Remineralization Effect of Nano Herbal Toothpaste With Two Kinds of Toothpaste Containing Fluoride and Bioactive Glass on Primary Enamel Lesions: An In Vitro Study

Evaluation of caries remineralization potential of toothpastes containing three remineralizing agents - calcium sucrose phosphate, β tricalcium phosphate and fluoro calcium phosphosilicate: An in vitro study

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