Comparative Evaluation of Wettability of Chlorhexidine, Betadine, and Herbal Mouthwash: An In Vitro Study

Harshitha, V RS; Jeevitha, M

doi:10.5005/jp-journals-10015-2278

World Journal of Dentistry

2023

DOI: 10.5005/jp-journals-10015-2278

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Comparative Evaluation of Wettability of Chlorhexidine, Betadine, and Herbal Mouthwash: An In Vitro Study

V RS Harshitha,

M Jeevitha

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2024

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Cited by 2 publications

References 29 publications

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Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process

Jeevitha,

Gurumoorthy,

Navarasu

2024

Journal of Pharmacy and Bioallied Sciences

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Wound healing is a multicellular and complicated process that strives to restore the skin’s barrier function. Different cell types, including keratinocytes, endothelial cells and fibroblasts collaborate for the process to complete. Tridax procumbens is a very important natural plant that is commonly found in the tropical region and has a wide range of pharmacological actions. In the present study the molecular docking was used to identify the activity of four compounds from T. procumbens to the selected receptor. The goal of this work was to anticipate the capacity of four T. procumbens compounds to interact with IL-1, IL-6, and TNF-α. Pyrx was used to run docking simulations for these compounds. Results of this study showed that all the four compounds showed interaction with selected target proteins. Among the four compounds, Tannic acid showed excellent binding and hydrogen bond interaction with all the selected target proteins. The results showed that T. procumbens compounds are effective anti-inflammatory agents. However, further research is required to validate the action of these molecules.

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Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process

Jeevitha,

Gurumoorthy,

Navarasu

2024

Journal of Pharmacy and Bioallied Sciences

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Anti-Inflammatory Activity and Free Radical Scavenging Activity of Tridax Procumbens Leaves-Based Chitosan Gel

Nandita,

Jeevitha,

Gurumoorthy

et al. 2024

Journal of Pharmacy and Bioallied Sciences

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Introduction: Tridax procumbens (TP) has been used as an anticoagulant and wound healer. Known by other names as Tridax daisy or coatbuttons, TP belongs to flowering plant species of Asteraceae family. The current study is conducted to analyze the anti-inflammatory and antioxidant activity of TP leaves extract-based chitosan (TPC) gel. Materials and Methods: Anti-inflammatory activity of TPC gel was assessed by bovine serum albumin (BSA) denaturation assay and egg albumin (EA) denaturation assay. Free radical scavenging activity was evaluated by DPPH (2,2-diphenyl-1-picrylhydrazyl) assay and hydroxyl radical scavenging (H2O2) assay. Results: Both BSA and EA assay showed that the TPC gel (test gel) demonstrated maximum inhibition at 50 μL concentration and lowest inhibition at 10 μL similar to commercially available gel. The antioxidant activity assays revealed that both standard and the test gel exhibited high inhibitory percentage at all tested concentrations. Conclusion: The anti-inflammatory and antioxidant assay results demonstrate that the investigated compounds, notably TP leaves extract-based chitosan gel, have the potential to be effective agents in moderating oxidative stress and lowering inflammation.

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Comparative Evaluation of Wettability of Chlorhexidine, Betadine, and Herbal Mouthwash: An In Vitro Study

Cited by 2 publications

References 29 publications

Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process

Computational Evaluation of Tridax Procumbens Phytoconstituents in Wound Healing Process

Anti-Inflammatory Activity and Free Radical Scavenging Activity of Tridax Procumbens Leaves-Based Chitosan Gel

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