Comparative Hemodynamic Consequences of Inflation Hold, PEEP, and Interrupted PEEP: An Experimental Study in Normal Dogs

MacDonnell, Kenneth F.; Lefemine, Armand A.; Moon, Hyung S.; Donovan, Daniel J.; Johnston, Richard P.

doi:10.1016/s0003-4975(10)64431-1

Cited by 9 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…24 In humans, cardiac output is decreased with positive pressure ventilation, 25 and positive pressure inspiratory hold has also been found to cause a decrease in cardiac output in dogs. 26 A weakness of our study was that inflation pressure was not numerically standardized. While this might have been preferable, the tidal volume and lung inflation pressure required to inflate alveoli fully is dependent on the size, compliance and airway resistance of the respiratory system.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The Effect of Manual Lung Inflation vs. Spontaneous Inspiration on the Cardiac Silhouette in Anesthetized Dogs

Webster¹,

Adams²,

Dennis³

2009

Vet Radiology Ultrasound

View full text Add to dashboard Cite

The purpose of this study was to assess radiographic heart size in anesthetized dogs, comparing radiographs made with the patient breathing spontaneously to radiographs obtained using positive pressure manual lung inflation. The hypothesis was that manual inflation would cause reduction in the cardiac size. With dogs in right recumbency a radiograph was made at peak spontaneous inspiration followed immediately a radiograph made with application of positive pressure manual inflation of the thorax. Cardiac size was assessed, both subjectively and objectively using the vertebral heart scale (VHS). Two hundred and six dogs were studied. Manual inflation resulted in a significantly greater degree of lung inflation assessed radiographically (P < 0.0001). The subjectively assessed heart size was significantly smaller in radiographs made with manual inflation, leading to different subjective categorization of heart size in 67 (32%) of dogs. The objectively measured VHS was also significantly smaller in the radiographs made using manual inflation by a mean of 0.24 of a vertebral length (95% CL of mean difference: -0.29, -0.19, P < 0.0001). A statistically significant reduction in subjective heart size and in VHS occurred with manual inflation of the lungs, and these differences may be clinically significant. Thus, if serial radiographs are obtained to assess cardiac size, the radiographic technique used should be the same.

show abstract

Section: Discussionmentioning

confidence: 99%

“…This may be due to decreased preload and increased extracardiac pressure during manual inflation 24 . In humans, cardiac output is decreased with positive pressure ventilation, 25 and positive pressure inspiratory hold has also been found to cause a decrease in cardiac output in dogs 26 …”

Section: Discussionmentioning

confidence: 99%