Comparative Histological Study of Mini Pig Skin After Chemical Peel and Dermabrasion

A Study of Dermabrasion and Chemical Peels in an Animal Model

“…It was their impression that the dermis does not undergo specific alterations secondary to dermabrasion and that when part of the dermis is removed by dermabrasion it does not regenerate. My results and those of Behin et al both show dermal injury deeper than can be accounted for by the reach of the fraise and regeneration following dermabrasion. Replacement of collagen that is injured but not actually removed by dermabrasion may account for much of the benefit achieved by dermabrasion in diminishing scars and smoothing out the surface of scarred skin.…”

Nonablative skin remodeling: Selective dermal heating with a mid-infrared laser and contact cooling combination

“…Finally, one should recall that dermal remodeling has been shown to occur at a depth of 100-400 m in chemical peeling, dermabrasion, and CO 2 laser ablation [28][29][30]. This is intuitively attractive, as this zone is where the bulk of solar elastosis is observed in photodamaged skin.…”

Skin anti-aging strategies

“…The mechanism by which the chemical peel takes effect is not clearly elucidated. An increase in collagen fiber content, water and GAG in the dermis has been reported 71 , 72 . There is a suggestion that improvements in skin elasticity and wrinkles after chemical peeling can be attributed to increase of Col-1 with or without Col-3, elastic fibers, as well of a dense rearrangement of collagen fibers 73 - 76 …”