Comparative histophotometric characteristics of the structural-metabolic heterogeneity of hepatocytes in peritonitis and limb gangrene

Abstract

Comparative histophotometric and correlation analysis was carried out to study dehydrogenase activity in hepatocytes of different acinar zones in peritonitis and gangrene of the lower extremities. Structural-metabolic disturbances of hepatocytes were found to be responsible for the weakened detoxicating function in patients with endotoxicoses. Special features of metabolic disturbances in the liver acini were demonstrated in peritonitis and limb gangrene.