Comparative immunology of agricultural birds

Schultz, Ursula; Magor, Katharine E.

doi:10.1016/b978-0-12-818708-1.00001-4

Cited by 2 publications

(2 citation statements)

References 290 publications

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“…In recent decades, researchers have, therefore, made an extensive effort towards understanding AIV disease progression in chickens and ducks to investigate the causes of disease susceptibility and resistance. A considerable number of comparative analyses regarding the genetic repertoire, gene functions, and evolutionary selection related to immune responses in different bird species, including chickens and ducks, have been performed and published [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. In this regard, pattern recognition receptors (PRRs) have been put in the spotlight due to their rapid initiation of immune responses to pathogens such as AIVs [7,10,22].…”

Section: Introductionmentioning

confidence: 99%

“…Specifically, they highlight the strong early response of PRRs and ISGs in duck tissues combined with a decrease in expression of proinflammatory cytokines in the lung and key components of leukocyte recruitment and complement pathways in the intestine [41]. For comprehensive overviews of differential gene expression and innate immunity related to AIV infection in chickens and ducks, we refer to [6][7][8]22].…”

Section: Introductionmentioning

confidence: 99%

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Comparative Investigation of Coincident Single Nucleotide Polymorphisms Underlying Avian Influenza Viruses in Chickens and Ducks

Bertram

Klees

Rajavel

et al. 2023

Biology

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Avian influenza is a severe viral infection that has the potential to cause human pandemics. In particular, chickens are susceptible to many highly pathogenic strains of the virus, resulting in significant losses. In contrast, ducks have been reported to exhibit rapid and effective innate immune responses to most avian influenza virus (AIV) infections. To explore the distinct genetic programs that potentially distinguish the susceptibility/resistance of both species to AIV, the investigation of coincident SNPs (coSNPs) and their differing causal effects on gene functions in both species is important to gain novel insight into the varying immune-related responses of chickens and ducks. By conducting a pairwise genome alignment between these species, we identified coSNPs and their respective effect on AIV-related differentially expressed genes (DEGs) in this study. The examination of these genes (e.g., CD74, RUBCN, and SHTN1 for chickens and ABCA3, MAP2K6, and VIPR2 for ducks) reveals their high relevance to AIV. Further analysis of these genes provides promising effector molecules (such as IκBα, STAT1/STAT3, GSK-3β, or p53) and related key signaling pathways (such as NF-κB, JAK/STAT, or Wnt) to elucidate the complex mechanisms of immune responses to AIV infections in both chickens and ducks.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparative Investigation of Coincident Single Nucleotide Polymorphisms Underlying Avian Influenza Viruses in Chickens and Ducks

Bertram

Klees

Rajavel

et al. 2023

Biology

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Cellular Composition of the Lymphoid Tissue of the Cecal Immune Formations in Ducks

Mazurkevych¹,

KLADNYTSKA²,

Usenko³

2022

Ukrainian journal of veterinary sciences

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Observing the quantitative and qualitative composition of immunocompetent cell populations of the lymphoid tissue of the immunogenic organs allows to determine the immune status of the organism in a certain age period. The object of research is determing the cellular composition of the lymphoid tissue of the cecal Peyer’s patches and cecal (apical) diverticula in ducks in age-concerned aspect. Material simples for research were selected from broiler ducks of the Blagovarsky cross. Cytological testss were performed on imprint specimens. Immunoblasts, lymphocytes, proplasmocytes, and plasmocytes, monocytes, and macrophages are distinguished among the cells of the lymphoid tissue of the cecal Peyer’s patches and the cecal diverticula. The content of these cells is not the same. Population of lymphocytes in imprint specimens is the biggest. It consists of subpopulations of small, medium, and large lymphocytes, the ratio is uneven. The largest is a subpopulation of small lymphocytes, and the smallest is a subpopulation of large ones. The total content of lymphocyte in cecal Peyer’s patches and cecal diverticula decreases with age of the subject ducks. The content of small and medium-sized lymphocytes in the cecal diverticula and small lymphocytes in the cecal Peyer’s patches as well decreases. Simultaneously, the content of large lymphocytes in the cecal diverticula, large and medium lymphocytes in the cecal Peyer’s patches increases. The immunoblasts content in the lymphoid tissue of the studied immune formations decreases with age of ducks, while the quantity of macrophages and monocytes conversely increases. Proplasmocytes and plasmocytes are detected in the lymphoid tissue of cecal Peyer’s patches and cecal diverticula from the age of 10 days in ducks. Their content increases significantly with the poultry age. Reticular cells observation if complicated due to their location under a dense layer of lymphoid cells. Fibroblasts, M-cells, erythrocytes, and granulocytes in imprint specimens are detected in trace amounts. The established changes in the cellular composition of the lymphoid tissue of the cecal Peyer’s patches and the cecal diverticula in ducks in the age-related aspect confirm the occurring immune reactions within them. Consideration of these changes will improve the effectiveness of anti-epizootic measures

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Comparative immunology of agricultural birds

Cited by 2 publications

References 290 publications

Comparative Investigation of Coincident Single Nucleotide Polymorphisms Underlying Avian Influenza Viruses in Chickens and Ducks

Comparative Investigation of Coincident Single Nucleotide Polymorphisms Underlying Avian Influenza Viruses in Chickens and Ducks

Cellular Composition of the Lymphoid Tissue of the Cecal Immune Formations in Ducks

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