2023
DOI: 10.21203/rs.3.rs-2434504/v1
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Comparative observations of the hemostatic effects of bio-zeolite gauze and QuickClot Combat Gauze on massive hemorrhage with coagulopathy

Abstract: BACKGROUND The presence of coagulopathy after bleeding negatively affects the hemostatic effects of gauze. In this study, we compared the hemostatic effects of bio-zeolite gauze (BZG) and QuickClot Combat Gauze (QCG) on massive hemorrhage complicated by coagulopathy. Methods In 30 rabbits, diluted coagulopathy was prepared by extraction of blood at a dose of 15 mL/kg body weight following infusion with saline three times the volume of blood loss. Then, simulated blast-induced pelvic injury was initiated to p… Show more

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