Comparative outcomes of radiofrequency ablation and cryoballoon ablation in dysplastic Barrett’s esophagus: a propensity score−matched cohort study

Agarwal, Siddharth; Alshelleh, Mohammad; Scott, Jamie; Dhaliwal, Lovekirat; Codipilly, Don C.; Dierkhising, Ross A.; Leggett, Cadman L.; Wang, Kenneth K.; Otaki, Fouad; Trindade, Arvind J.; Iyer, Prasad G.

doi:10.1016/j.gie.2021.09.037

Cited by 18 publications

(24 citation statements)

References 31 publications

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“…Cryotherapy is associated with a 9%-12% stricture rate. There are currently no randomized trial data comparing cryotherapy and RFA, but a recent nonrandomized multicenter study reported comparable rates of CED and CEIM in patients with dysplastic BE treated with RFA and cryoballoon ablation with higher stricture rates in the cryoballoon cohort (213). Recommendation.…”

Section: Recommendationmentioning

confidence: 99%

Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline

et al. 2022

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Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly lethal cancer with an increasing incidence over the last 5 decades. These revised guidelines implement Grading of Recommendations, Assessment, Development, and Evaluation methodology to propose recommendations for the definition and diagnosis of BE, screening for BE and esophageal adenocarcinoma, surveillance of patients with known BE, and the medical and endoscopic treatment of BE and its associated early neoplasia. Important changes since the previous iteration of this guideline include a broadening of acceptable screening modalities for BE to include nonendoscopic methods, liberalized intervals for surveillance of short-segment BE, and volume criteria for endoscopic therapy centers for BE. We recommend endoscopic eradication therapy for patients with BE and high-grade dysplasia and those with BE and low-grade dysplasia. We propose structured surveillance intervals for patients with dysplastic BE after successful ablation based on the baseline degree of dysplasia. We could not make recommendations regarding chemoprevention or use of biomarkers in routine practice due to insufficient data.

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Section: Recommendationmentioning

confidence: 99%

Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline

et al. 2022

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“…In the CBA group, the stricture rate was higher (10 versus 4.4%). Histological outcomes of CBA and RFA were comparable [1 ▪ ].…”

Section: Early Barett's Neoplasiamentioning

confidence: 85%

“…Agarwal et al [1 ▪ ] compared the effectiveness and safety of CBA and RFA within a cohort study. Median follow-up was 2 years [1 ▪ ].…”

Section: Early Barett's Neoplasiamentioning

confidence: 99%

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Thermal ablative therapies in the gastrointestinal tract

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2023

Current Opinion in Gastroenterology

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Purpose of review Thermal ablatives therapies have seen an expanding role in gastrointestinal endoscopy during the last years. The aim of this review is to give an overview of the currently available techniques. Recent findings In the upper gastrointestinal tract, mainly in early Barrett's neoplasia, endoscopic ablation strategies ranging from RFA to Hybrid-APC are, together with resection strategies, the main part of the armamentarium. In the small intestine, argon plasma coagulation (APC) can be effectively used for the treatment of angiodysplasias. In the lower gastrointestinal tract, APC and RFA are mainly used. In tumour obstruction, thermal ablation is used to reopen the lumen. The selection of available techniques is still increasing. Summary The variety of ablation techniques enables the endoscopist to choose the appropriate ablation tool for each individual patient.

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“…40 The main ablative therapies are RFA, 35,41 cryotherapy, 42 and argon plasma coagulation. 43 Although histologic outcomes of cryoballoon ablation and RFA seem to be comparable, 44 RFA is currently the most commonly used ablative therapy with demonstrated safety and efficacy for both CEIM and CED. 35,41 Cryotherapy demonstrated similar rates of CED but lower rates of CEIM when compared with RFA.…”

Section: Meeting Summariesmentioning

confidence: 99%