“…Over the years, many groups have applied proteomic approaches to analyse differences in the human NS proteome mostly involving allergic rhinitis (Tomazic et al, 2013 andTomazic et al, 2014) and chronic rhinosinusitis (Upton et al, 2011) with healthy controls. Most of the proteins identified in human NS (Casado et al, 2005) were similar with the nasal proteins detected in cattle with many proteins involved in innate and acquired immunity ( Figure 5.7).…”