In this paper, a new integrated control system via visual-servoing and cascaded proportional derivative (PD) controllers for an autonomous hexacopter is proposed. The spherical image based visual servoing is designed to control the hexacopter to the desired pose with respect to an arbitrary target in three-dimensional (3D) workspace based on images captured. Meanwhile, the cascade-PD controller is designed to stabilize and to control the altitude and Bourquardez, O., Mahony, R., Guenard, N., Chaumette, F., Hamel, T., Eck, L.