Comparative Screening of the Possible Activity of Rhopilema nomadica Jellyfish Venom Against Different Protista and Invertebrates

Rashed et al., Hadeer Abd El-hak

doi:10.21608/ejabf.2023.321216

Egypt. J. of Aquatic Biolo. and Fish.

2023

DOI: 10.21608/ejabf.2023.321216

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Comparative Screening of the Possible Activity of Rhopilema nomadica Jellyfish Venom Against Different Protista and Invertebrates

Hadeer Abd El-hak Rashed et al.

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2024

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Toxocara canis: Prospective activity of Quercetin and venom of Cassiopea andromeda (Cnidaria: Cassiopeidae) against third‐stage larvae in vitro

Elmahy,

Moustafa,

Radwan

2024

J Exp Zool Pt A

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Toxocariasis is a zoonotic parasitic infection with worldwide distribution and high impact on human health. It has a limited clinical resolution with the available drugs, making it challenging to treat. Quercetin, which possesses biological and pharmacological qualities including antiparasitic, antioxidant, and anticancer activities, is a possible substitute for the current medications. Marine invertebrates can produce a vast array of different molecules, many of which are biologically active substances with distinct characteristics. In this study, we assessed the in vitro nematocidal effect of both quercetin and venom of Cassiopea andromeda (jellyfish) against third larvae of Toxocara canis. In microplates with Roswell Park Memorial Institute‐1640 medium, larvae were incubated with ethanolic extract of quercetin (0.01, 0.02, 0.05, 0.08, 0.1, 0.25, and 0.5 mM/mL) and water extract of C. andromeda venom (15, 20, 25, 30, 35, 40, and 60 µg/mL) to evaluate their larvicidal effect. A scanning electron microscopy has investigated the possible effect of lethal concentration (LC90) of both extracts on the body wall of cultivated larvae, in comparison with those cultivated in albendazole. Our study revealed the effects of both quercetin and C. andromeda venom exposure on the mortality rate and the ultrastructure of T. canis third larva in comparison with control and albendazole‐treated groups.

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Toxocara canis: Prospective activity of Quercetin and venom of Cassiopea andromeda (Cnidaria: Cassiopeidae) against third‐stage larvae in vitro

Elmahy,

Moustafa,

Radwan

2024

J Exp Zool Pt A

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show abstract

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Comparative Screening of the Possible Activity of Rhopilema nomadica Jellyfish Venom Against Different Protista and Invertebrates

Cited by 1 publication

References 14 publications

Toxocara canis: Prospective activity of Quercetin and venom of Cassiopea andromeda (Cnidaria: Cassiopeidae) against third‐stage larvae in vitro

Toxocara canis: Prospective activity of Quercetin and venom of Cassiopea andromeda (Cnidaria: Cassiopeidae) against third‐stage larvae in vitro

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