Comparative sensitivity of liver monoamine oxidases of frog and whitefish to some tricyclic compounds

Morphological alterations and acetylcholinesterase and monoamine oxidase inhibition in liver of zebrafish exposed to Aphanizomenon flos-aquae DC-1 aphantoxins

“…The present findings showed that MAO activity in zebrafish liver might be significantly reduced by aphantoxin exposure, suggesting reduced inactivation of monoaminergic neurotransmission. Several recent studies have reported MAO inhibition in the livers of fish and other aquatic animals (lamprey Lampetra fluviatilis) induced by several chemicals, thus strengthening the present findings (Basova and Yagodina, 2011;Yagodina and Basova, 2013).…”

Respiratory toxicity of cyanobacterial aphantoxins from Aphanizomenon flos-aquae DC-1 in the zebrafish gill

“…The gills are regulated and innervated by sympathetic nerves of the autonomic/splanchnic nerve system, which includes monoaminergic/adrenergic neurons (Saltys et al, 2006). Several previous studies have investigated the inhibition of MAO activity as a result of toxicant exposure in the brain and liver of fish (Nam et al, 2010;Basova and Yagodina, 2011). However, there is a lack of published data regarding the influence of toxicant exposure on MAO activity in the gills of fish.…”