Comparative study between cyanoacrylate tissue adhesive versus skin sutures in closure of wound in 60 operated cases of open inguinal hernia

Manza, Jawansing T.; Maisuria, Rushabh S.; Chaudhari, Devendra R.; Dave, Divyang N.; Gajra, Yatin B.; Patel, Daxesh P.

doi:10.18203/2349-2902.isj20181608

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…The most widespread wound healing methods in clinical practice are surgical suture and stapler binding, but such methods may cause suffering to patients and sometimes need to be achieved by anesthesia. Besides, traditional sutures perform poorly when sutured on soft tissue [1,2]. In response to these problems, medical adhesives came into being.…”

Section: Introductionmentioning

confidence: 99%

Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions

et al. 2021

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Bio-adhesives are essential for wound healing because of their convenience and safety. Although widely used as biomaterials, silk fibroin’s (SF’s) further application as bio-adhesive is hindered due to its weak stickiness with tissue and slow gelation speed. Here, a dopamine-modified SF-based bio-adhesive is fabricated by using genipin as the chemical cross-linking agent. Furthermore, metal ions have been used to adjust the adhesion property of the bio-adhesive. The experimental results shows that the dopamine-modified SF-based composite holds a better stickiness except slow gelation speed. The doping of Cu2+ and Fe3+ can accelerate the gelation of the bio-adhesive. Compared with Cu2+, Fe3+ has a stronger effect on the gelation speed of the bio-adhesive, which is positive correlative to the concentration of Fe3+. The adhesive has injectability and degradability. In addition, the SF-based adhesive has good biocompatibility and good improvement for cell migration in vitro. The SF-based bio-adhesive holds potential application in the field of rapid fixation of wounds.

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Section: Introductionmentioning

confidence: 99%

Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions

et al. 2021

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“…Using cyanoacrylate adhesive, the incision healed with a single linear scar that is more esthetically pleasing than a suture scar. When cyanoacrylate glue is used instead of sutures, wound dehiscence occurs more frequently [12].…”

Section: Tripathi and Dixitmentioning

confidence: 99%

Comparative Evaluation of Efficacy of Cyanoacrylate and Suture Material in the Management of Operative Skin Wounds

TRIPATHI¹,

DIXIT²

2022

Asian J Pharm Clin Res

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Objective: Closing wounds are a fundamental aspect of surgery. Both patients and surgeons hope that no scars remain once a wound has healed. This study examined the effectiveness of cyanoacrylate and suture material in closing operational skin wounds in terms of time required for closure of the operative incision and problems associated with it. Methods: Forty-two individuals who had emergency surgery participated in this comparative analysis. The study evaluated how the identical patient’s abdominal incisions were closed on the skin. Relevant surgical information, such as signs of inflammation, discomfort, possible discharge, wound dehiscence, and sinus, was recorded both during and after the operation. Results: In the adhesive application group, it took 1.5 min (95 s), but it took 4.1 min (248 s) in suturing group for the closure of a <5-cm incision. Of the 32 patients in the adhesive group, 4 (12.5%) showed erythema and warmth, 3 (9.3%) showed discomfort, and 6 (18.7%) showed discharge. All other problems, excluding dehiscence, were less severe in the sticky group. Conclusion: For patients undergoing emergency laparotomies, cyanoacrylate appears to be a safe and cost-effective alternative to sutures. For a conclusive outcome, a high number of case groups are needed, but the observed results were only on a small number of case groups.

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“…and glue application time of 1.3min. Jawasing Manza et al 17 reported suturing time of 7 minutes and glue application time of 3 minutes.…”

Section: Skin Closure Timementioning

confidence: 99%

Comparative Study Between 2 Butyl Cyanoacrylate Versus Conventional Sutures in Skin Closure of Inguinal Hernia Patients

Ashok¹,

Mandapat²,

Palaniappan³

2019

jebmh

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BACKGROUNDSkin sutures are known as the signature of a surgeon. However, in recent times conventional suturing is being replaced by newer methods of skin closure. The commonest of them being skin staples. There are numerous other methods available like adhesives tapes and adhesive glues. Skin staples gained popularity due to the less time needed to apply the staples and the cost was comparative to the sutures used. Use of adhesive glue was restricted due to the cost. This study was designed to compare the outcomes between conventional suture closure and 2-butyl cyanoacrylate glue closure of skin after inguinal hernia surgery. MATERIALS AND METHODSThis was a prospective case-controlled study with a sample size of 50 done in Pondicherry Institute of medical sciences over a period of 18 months. Patients between the ages of 25 to 70 undergoing elective inguinal hernia surgery were included in this surgery. Patients with recurrent inguinal hernia and who had features of strangulation were excluded. RESULTSThe mean age in suture group was 48.24 and in skin glue group it was 47.92. 2 out of 25 (8%) in glue group and 7 out of 25 (18%) in the sutures group had erythema and induration 48 hours after surgery. 1 (4%) patient had serous discharge with partial wound dehiscence in glue group while there was none in suture group. 2 butyl cyanoacrylate was costlier by Rs. 120 than sutures per wound. CONCLUSIONThe use of tissue adhesive was associated with shorter closure time. Pain was much less in patients for whom skin closure was performed using skin glue and as such comparatively less analgesics were required post operatively. Glue was marginally costly than conventional sutures. KEYWORDS 2-Butyl Cyanoacrylate, Skin Closure, Inguinal Hernia HOW TO CITE THIS ARTICLE: Ashok AJ, Jacob JM, Palaniappan NK. Comparative study between 2 butyl cyanoacrylate versus conventional sutures in skin closure of inguinal hernia patients.

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Comparative study between cyanoacrylate tissue adhesive versus skin sutures in closure of wound in 60 operated cases of open inguinal hernia

Cited by 4 publications

References 5 publications

Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions

Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions

Comparative Evaluation of Efficacy of Cyanoacrylate and Suture Material in the Management of Operative Skin Wounds

Comparative Study Between 2 Butyl Cyanoacrylate Versus Conventional Sutures in Skin Closure of Inguinal Hernia Patients

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