Comparative study between doses of intrathecal morphine for analgesia after caesarean

Abstract

Intrathecal morphine 50 μg provides the same quality of analgesia as 100 μg, with a lower incidence of side effects.

The analgesic efficiency of transversus abdominis plane (TAP) block after caesarean delivery

“…In the presented study, subarachnoid analgesia was obtained using 0.5% hyperbaric bupivacaine and 0.25% hyperbaric bupivacaine was used for the TAP block. Opioids were not administered into the subarachnoid space due to lack of sufficient postoperative monitoring of the patients and in order to avoid possible complications, such as pruritus and difficulties in passing urine [9,10]. The ultrasound-guided TAP block is a simple and safe analgesic technique.…”

Randomized study of postcesarean analgesia with intrathecal morphine alone or combined with clonidine

“…Despite small intrathecal doses of morphine provide analgesia after cesarean, more than 59% of patients have moderate-to-severe pain during the first 12 hours after surgery [1][2][3][4]35,36]. In addition, the use of neuraxial opioids has been related to side effects varying in incidence and intensity, according to the dose level [2,3,35,37].…”

“…In addition, the use of neuraxial opioids has been related to side effects varying in incidence and intensity, according to the dose level [2,3,35,37]. Related to intrathecal opioids, it is essential to find alternatives to improve analgesia and to reduce side effects; 1 option is the combination of local anesthetics with opioids and clonidine because these drugs have synergistic effects [8,[16][17][18][19][20][21][22][23][24][25][26][27]31].…”

Post-caesarean analgesia: What is new?

“…[3] A further lower dose of 50 µg with 100 µg ITM was evaluated in two studies and found to be equally efficacious. [45] These results showed that there is no direct relationship between the dose of ITM and the quality of analgesia. Similar results were demonstrated in previous studies by other investigators.…”