Comparative Study Between Using Antracycline Based and Taxane Based Regimens as First Line Therapy for Advanced and Metastatic Gastric Cancer

Abstract

Introduction: ECF with continuous infusional 5-fluorouracil (5-FU) is a well-established chemotherapy regimen in advanced gastric cancer. However, several modifications have been done on this regimen to make more convenient, some of these trials showed comparable results with the original one, others tried to use Taxane instead of Epirubicin the form of Paclitaxel as a first line therapy as it showed also comparable results with Docetaxel, nevertheless it is cheaper and more tolerable regimen.