Comparative study evaluating the efficiency of cooled and uncooled single-treatment MWA in thyroid nodules after a 3-month follow up

Mader, Alexander; Tanha, Nadine Farivar; Happel, Christian; Korkusuz, Yücel; Grünwald, Frank

doi:10.1016/j.ejro.2017.01.004

Cited by 12 publications

(12 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Secondly, cyst and solid mixed nodules were also enrolled in this study, we conducted MWA after liquid was aspirated completely for such nodules, that will possibly improve the value of VRR [26]. Moreover, it is not a prospective study, and we retrospectivly compared the nodule volume before and after procedure.…”

Section: Discussionmentioning

confidence: 99%

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

Gong

Zhou

et al. 2017

Endocr J

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

Gong

Zhou

et al. 2017

Endocr J

View full text Add to dashboard Cite

“…Retrospective studies describe a 74.6-90.0% mean volume reduction after 1 year [22], and in 2 meta-analyses volume reduction was 74% at 6 months and 89% at 12-month follow-up [65,66]. However, in a prospective study comparing the performance of cooled versus uncooled MWA applicators, the mean reduction rates at 3 months were only 40 and 29%, respectively [67]. As with LTA and RFA, this variability in technique efficacy could be due to the heterogeneous structure of the nodules of the patients enrolled in the studies.…”

Section: Microwave Ablationmentioning

confidence: 99%

2020 European Thyroid Association Clinical Practice Guideline for the Use of Image-Guided Ablation in Benign Thyroid Nodules

et al. 2020

View full text Add to dashboard Cite

Standard therapeutic approaches for benign thyroid lesions that warrant intervention are surgery for cold and either surgery or radioiodine for autonomously functioning thyroid nodules (AFTN). Image-guided thermal ablation (TA) procedures are increasingly proposed as therapy options for selected clinical conditions. Due to mounting scientific evidence and widening availability, ETA considered it appropriate to develop guidelines for the use of TA in adult patients. TA procedures are well tolerated, but a dedicated training of the operators is required and information on possible complications needs to be shared with the patients. The following factors should be considered when weighing between observation, surgery, and TA for benign thyroid nodules. In solid non-hyperfunctioning nodules, TA induces a decrease in thyroid nodule volume, paralleled by improvement in symptoms. Nodule re-growth is possible over time and may necessitate repeat treatment, or surgery, in a dialogue with the patient. In AFTN, radioactive iodine is the first-line treatment, but TA may be considered in young patients with small AFTN due to higher probability of restoring normal thyroid function and avoidance of irradiation. In cystic nodules, ethanol ablation (EA) is the most effective and least expensive treatment. TA may be considered for cystic lesions that relapse after EA or have a significant residual solid component following drainage and EA. TA should be restricted to benign lesions that cause symptoms or cosmetic concern. Presently, laser and radiofrequency ablation are the most thoroughly assessed techniques, with similar satisfactory clinical results. Microwaves and high-intensity focused ultrasound therapy options remain to be fully evaluated.© 2020 European Thyroid Association Published by S. Karger AG, Basel Recommendation 1. In adult patients with benign thyroid nodules that cause pressure symptoms and/or cosmetic concerns and decline surgery, image-guided TA should be considered as a costand risk-effective alternative option to surgical treatment or observation alone (1, ØØOO).Recommendation 2. We recommend against the use of TA for asymptomatic lesions (1, ØØØO).

show abstract

“…This technique can cause coagulative necrosis of the lesion tissue via high temperature heating, enabling minimally invasive local inactivation of the lesion. [ 2 , 3 ] The essence of MWA is the electromagnetic wave. The magnetron in the microwave generator produces microwaves, which can raise the local temperature to 60 to 100 °C and leads to protein denaturation.…”

Section: Introductionmentioning

confidence: 99%

Horner syndrome as a complication after thyroid microwave ablation

Zhang

Ren

et al. 2018

Medicine

View full text Add to dashboard Cite

Rationale:Horner's syndrome (HS) can present as a complication of thyroid surgery, particularly after thyroid microwave ablation (MWA). HS presents clinically with eyelid ptosis, miosis, enophthalmos, anhidrosis, and vascular dilatation, all of which result from a damaged oculosympathetic chain. We aimed to try to avoid such devastating symptoms in future cases by exploring reasons for the destruction of the cervical sympathetic trunk.Patient concerns:HS has previously been reported in the literature as a complication of thyroid surgery. Here, we report the case of a 44-year-old female patient who presented with miosis and eyelid ptosis following thyroid MWA.Diagnoses:This patient was subsequently diagnosed with HS.Interventions:Mecobalamin was administered immediately.Outcomes:After 5 months of follow up, the patient's miosis and ptosis was incompletely relieved.Lessons:Although HS is a rare complication of thyroid MWA, surgeons must be aware of the anatomic relationship of the cervical sympathetic trunk and thyroid gland with adjacent structures. Moreover, we hope this case presentation enables surgeons to take measures to minimize the possibility of oculosympathetic damage. Long-term follow up and comprehensive assessments are important for the patient's prognosis.

show abstract

Comparative study evaluating the efficiency of cooled and uncooled single-treatment MWA in thyroid nodules after a 3-month follow up

Abstract: HighlightscMWA and uMWA both lead to a significant reduction of thyroid nodule volume.Patient pain level during uMWA is significantly higher than during cMWA.cMWA reduces the risk of side effects.Single-treatment session shows comparable results to multiple treatment sessions.

Cited by 12 publications

References 26 publications

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

US-guided percutaneous microwave ablation for the treatment of benign thyroid nodules

2020 European Thyroid Association Clinical Practice Guideline for the Use of Image-Guided Ablation in Benign Thyroid Nodules

Horner syndrome as a complication after thyroid microwave ablation

Contact Info

Product

Resources

About