Comparative study in the management of allergic rhinitis in children using LED phototherapy and laser acupuncture

Moustafa, Yousry; Kassab, Ahmed Nazmi; Sharnoubi, Jehan el; Yehia, Hala

doi:10.1016/j.ijporl.2013.01.006

Cited by 23 publications

(23 citation statements)

References 26 publications

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“…The low cost of LEDs compared to lasers, and their ubiquity, suggests that LED-based devices will remain preferred by many over lasers, unless there is strong evidence that intervention with lasers yield superior results. Consequently, the photobiomodulative effect of LEDs relative to lasers has been questioned by many [1,2], with some asserting that laser diodes are more effective than LEDs [3,4] and others claiming that LEDs are as effective as lasers [1,[4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro

et al. 2015

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It has long been argued that light from a laser diode is superior to light from a light-emitting diode (LED) in terms of its effect on biological tissues. In order to shed light on this ongoing debate, we compared the antimicrobial effect of light emitted from a 405-nm LED with that of a 405-nm laser on methicillin-resistant Staphylococcus aureus (MRSA) at comparable fluences. We cultured 5 × 10(6) CFU/ml MRSA on tryptic soy agar and then irradiated culture plates once, twice, or thrice with either LED or laser light using 40, 54, 81, or 121 J/cm(2) fluence at 15-, 30-, or 240-min time interval between irradiation. Cultures were incubated immediately after irradiation at 37 °C for 24 h before imaging and counting remnant bacterial colonies. Regardless of the device used, LED or laser, irradiation at each fluence resulted in statistically significant bacterial growth suppression compared to non-irradiated controls (p < 0.0001). The antimicrobial effect of both light sources, LED and laser, was not statistically different at each fluence in 35 of the 36 experimental trials. Bacterial growth suppression achieved with either source of light increased with repeated irradiation, particularly at the 15- or 30-min treatment time interval. Thus, we conclude that the antimicrobial effect of 405-nm laser and 405-nm LED on MRSA is similar; neither has a superior antimicrobial effect when compared to the other.

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Section: Introductionmentioning

confidence: 99%

The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro

et al. 2015

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“…In human medicine, this therapeutic approach is common in paediatrics and in patients with needle phobias [ 10 , 12 ]. In veterinary medicine, this technique may represent a viable alternative for those patients where introduction of a needle may be hindered by the behavior of the animal.…”

Section: Introductionmentioning

confidence: 99%

Laser Acupuncture for Postoperative Pain Management in Cats

Marques

Cassu

Nascimento

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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The aim of this study was to evaluate laser acupuncture as an adjuvant for postoperative pain management in cats. Twenty cats, undergoing ovariohysterectomy, were sedated with intramuscular (IM) ketamine (5 mg kg−1), midazolam (0.5 mg kg−1), and tramadol (2 mg kg−1). Prior to induction of anaesthesia, the subjects were randomly distributed into two groups of 10 cats: Laser: bilateral stomach 36 and spleen 6 acupoints were stimulated with infrared laser; Control: no acupuncture was applied. Anaesthesia was induced using intravenous propofol (4 mg kg−1) and maintained with isoflurane. Postoperative analgesia was evaluated by a blinded assessor for 24 h following extubation using the Dynamic Interactive Visual Analogue Scale and Multidimensional Composite Pain Scale. Rescue analgesia was provided with IM tramadol (2 mg kg−1), and the pain scores were reassessed 30 min after the rescue intervention. If the analgesia remained insufficient, meloxicam (0.2 mg kg−1 IM, single dose) was administered. Data were analyzed using t-tests, the Mann-Whitney test, and the Friedman test (P < 0.05). The pain scores did not differ between groups. However, postoperative supplemental analgesia was required by significantly more cats in the Control (5/10) compared with the Laser group (1/10) (P = 0.038). Laser acupuncture reduced postoperative analgesic requirements in cats undergoing ovariohysterectomy.

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“…Since the aim of this study is to determine preliminary feasibility, there will be no sample size calculation. We will conduct a pilot study with a sample size of 80 participants (40 in the intranasal phototherapy group and 40 in the acupuncture group) based on the previous pilot study, [ 23 ] and we predict that the drop-out rate will be 20%. A total of 64 patients are predicted to complete the study.…”

Section: Methodsmentioning

confidence: 99%

Effects and safety of intranasal phototherapy for allergic rhinitis

et al. 2020

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Introduction: Allergic rhinitis (AR) is an immunoglobulin E (Ig E)-mediated inflammatory disease. Intranasal phototherapy is a promising treatment modality because it has a profound immunosuppressive effect, but the evidence of its use for AR is insufficient. Therefore, rigorously designed randomized controlled trials (RCTs) are needed. Our objective is to describe the protocol for an RCT to assess the effects and safety of intranasal phototherapy for the treatment of AR. Methods and analysis: This is a study protocol for a single-center, randomized, parallel (acupuncture-controlled), open-label, investigator-initiated, pilot study. A total of 80 patients with AR will be randomly assigned to the intranasal phototherapy or acupuncture group at a 1:1 ratio. The participants will receive intranasal phototherapy with medical or acupuncture treatment for 20 minutes, 3 times a week for 4 weeks. The primary outcome will be the mean change in the total nasal symptom score (TNSS) from baseline to 4 weeks. The secondary outcomes will include the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) score, Nasal Endoscopy Index, total serum immunoglobulin E (Ig E) level and eosinophil count. Discussion: The findings of this study will provide the basis for the design and implementation of RCTs investigating the effects and safety of intranasal phototherapy for AR. Additionally, it will provide preliminary evidence of intranasal phototherapy for use in AR. Trial registration: This study was registered at the Korean National Clinical Trial Registry, Clinical Research Information Service (KCT0004079).

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Comparative study in the management of allergic rhinitis in children using LED phototherapy and laser acupuncture

Cited by 23 publications

References 26 publications

The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro

The relative antimicrobial effect of blue 405 nm LED and blue 405 nm laser on methicillin-resistant Staphylococcus aureus in vitro

Laser Acupuncture for Postoperative Pain Management in Cats

Effects and safety of intranasal phototherapy for allergic rhinitis

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