To simulate the influence of rainfall on the internal forces of expansive soil slope retaining structures, an approximate calculation method for the humidity stress field of expansive soil is proposed in this study. Considering both rainy and non-rainy conditions, on a high expansive soil slope, a numerical model is constructed for a combining supporting structure, which is composed of upper and lower anti-sliding piles and anchor rods/cable frames. Furthermore, the distribution of internal forces in the retaining structure is studied, and design optimization is performed. The research findings reveal that the bending moment profile along the longitudinal axis of the lower anti-sliding pile demonstrates a distinctive “W” pattern, which is characterized by initial reduction, following augmentation, a subsequent reduction, and final amplification. In contrast, the upper anti-sliding pile experiences an ascending trend, followed by a descending trend, and then a subsequent ascending trend. Interestingly, the introduction of rainfall grants an escalation in both the shear force exerted along the entire length of the upper and lower anti-sliding piles and the bending moment encountered by the lower anti-sliding pile. The determination of the internal force distribution of the expansive soil slope retaining structures under different conditions, using the proposed calculation method, provides a further optimization in their design.