Comparative study of effects of two bile acid derivatives on Staphylococcus aureus by multiple analytical methods

Kong, Weijun; Jin, Cheng; Xiao, Xiaohe; Yan, Zhao; Li, Zulun; Zhang, Ping; Liu, Wei; Li, Xingfeng

doi:10.1016/j.jhazmat.2010.03.064

Cited by 27 publications

(14 citation statements)

References 36 publications

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“…The curve in Fig. 1 expressed typical growth characteristics of S. aureus without other substances, which could be divided into five phases, that is, the Resistance of S. aureus to antibacterial agents exponential growth phase, the transition phase, the plateau phase, and the decline phase [7]. The peak in the curve represented the maximum heat-output in the exponential growth phase, from which some quantitative information was obtained.…”

Section: Resultsmentioning

confidence: 99%

“…However, due to the overlapping of information and different change trends of the parameters, it may be difficult to get accurate conclusions [7]. So, some suitable statistical methods are introduced to solve this problem by figuring out the main parameter(s).…”

Section: Principal Component Analysismentioning

confidence: 99%

“…Recently, more and more attentions have been paid on plant extracts and their constituents, which have expressed their manifested antibacterial effects [6][7][8]. Dracontomelon dao (Renmianzi in Chinese), an ancient and traditional medicinal plant of family Anacardiaceae, is mainly distributed in Guangdong, Guangxi, and Hainan provinces of China.…”

Section: Introductionmentioning

confidence: 99%

“…Through analyzing the information, the effects of the tested substances on bacterial growth could be evaluated accurately, providing helpful references for the potential use of them as novel antibacterial agents. With high accuracy and sensitivity, and little time consumption, recently, microcalorimetry has been successfully used to evaluate the antibacterial properties of some medicinal plants, products, and their major components on S. aureus [7,14,17,18], which provided some useful references for screening novel antibacterial agents rapidly and shortening the development cycle.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Microcalorimetry coupled with principal component analysis for investigating the anti-Staphylococcus aureus effects of different extracted fractions from Dracontomelon dao

Yan

Liu

et al. 2014

J Therm Anal Calorim

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With the prevalence resistance of Staphylococcus aureus to antibacterial agents, developing novel antibacterial agents is urgent. Recently, plant extracts have got more focus. In this study, the power-time curves produced by S. aureus under the action of the four extracted fractions (PE, CHCl 3 , EtOAc, and n-BuOH fractions) from the leaves of Dracontomelon dao were determined by microcalorimetry, and then some quantitative parameters, such as growth rate constant k, total heat output Q t , maximum heat-output power P m , and the appearance time t m were obtained. By analyzing the parameters using principal component analysis, the anti-S. aureus effects of the four fractions were systematically evaluated and compared. Meanwhile, the total flavonoid contents in these fractions were analyzed. The results have evidenced that different fractions using various extraction solvents expressed various anti-S. aureus effects, and the inhibitory effects were presented in a flavonoid content-dependent manner. The EtOAc fraction with the highest total flavonoid content (41.86 %) expressed the strongest anti-S. aureus effect with halfinhibitory concentration (IC 50 ) of 83.93 lg mL -1 , which might be applied as a novel antibacterial agent in practice for some infectious diseases. In addition, the microcalorimetric method should be strongly suggested in screening for novel antibacterial agents for fighting against pathogenic bacteria.

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Section: Resultsmentioning

confidence: 99%

Section: Principal Component Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Microcalorimetry coupled with principal component analysis for investigating the anti-Staphylococcus aureus effects of different extracted fractions from Dracontomelon dao

Yan

Liu

et al. 2014

J Therm Anal Calorim

Self Cite

View full text Add to dashboard Cite

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“…It is obvious that microcalorimetry is a very useful analytical tool for performing fundamental studies of the growth metabolism of a cell. It has been extensively applied to investigate the state of interaction between drug and cell with much useful information in both qualitative and quantitative ways [1][2][3][4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Influences of levofloxacin salts on the metabolism of Escherichia coli by microcalorimetry

Wang

Sun

et al. 2012

J Therm Anal Calorim

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A microcalorimetric technique was used to evaluate the influence of both Levofloxacin lactate in sodium chloride injection (drug A) and Levofloxacin hydrochloride in sodium chloride injection (drug B) on the metabolism of Escherichia coli. By means of an isothermal calorimeter and ampoule method at 37°C, the power-time curves of E. coli growth were obtained under different conditions. The parameters such as the growth rate constant k, maximum power output P m , time t m corresponding to the maximum power output and inhibitory ratio I of these two drugs were obtained. The results reveal that the inhibitory abilities enhance with increasing concentrations of the two drugs. The critical growth concentration and the halfinhibitory concentration IC 50 were 0.15 and 0.079 lg mL -1 (for drug A), 0.13 and 0.061 lg mL -1 (for drug B), respectively. These results show the drug A has slightly better inhibitory effect on E. coli than that of drug B.

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Exploring medium‐term impact of oxide nanoparticles on soil microbial activity by isothermal microcalorimetry and urease assay

Yao

Russel

et al. 2015

Env Prog and Sustain Energy

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The entry of oxide nanoparticles (NPs) into the environment mandates study of their impact on the soil ecosystem. This study explored the medium‐term impact (about 120 days) of oxide NPs on the soil microbial community and urease activity through isothermal microcalorimetry and enzyme assay. The soil samples were separately treated with four types of oxide NPs (ZnO, Al2O3, TiO2, and SiO2 NPs) at 1 μg/g soil or 500 μg/g soil compared with a control, and incubated for up to 120 days. Except for some sort of acute toxicity, the NPs have no significant deleterious effect (P > 0.05) on the soil microbial community and urease activity along with the incubation time lengthening, which suggests that incubation time played a more essential role in modifying the antibacterial activity than the nature of oxide NPs. That is the medium‐term impacts of oxide NPs on the soil microbial process was not very simple and monofactorial. © 2015 American Institute of Chemical Engineers Environ Prog, 35: 395–403, 2016

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Comparative study of effects of two bile acid derivatives on Staphylococcus aureus by multiple analytical methods

Cited by 27 publications

References 36 publications

Microcalorimetry coupled with principal component analysis for investigating the anti-Staphylococcus aureus effects of different extracted fractions from Dracontomelon dao

Microcalorimetry coupled with principal component analysis for investigating the anti-Staphylococcus aureus effects of different extracted fractions from Dracontomelon dao

Influences of levofloxacin salts on the metabolism of Escherichia coli by microcalorimetry

Exploring medium‐term impact of oxide nanoparticles on soil microbial activity by isothermal microcalorimetry and urease assay

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