Comparative study of hysteroscopy with ultrasonography and its correlation with histopathology in cases of abnormal uterine bleeding in perimenipausal women

Abstract

Background: The aim was to compare the diagnostic efficacy of ultrasonography (USG) and hysteroscopy in detecting uterine abnormalities in abnormal uterine bleeding (AUB) by correlating the results with histopathological examination.Methods: This prospective study was conducted among women attending gynecological OPD of Subharti medical college, Meerut over a period of two years from October 2019 to August 2021. A total of 100 perimenopasual women with AUB attending obstetrics and gynaecology OPD were included in this study. All patients underwent transvaginal scan to note down the endometrial thickness and to rule out uterine and adnexal pathology. All the patients underwent diagnostic hysteroscopy, followed by a biopsy of the endometrium using a curette. The endometrium was sent to the pathologist. Findings of these diagnostic modalities then correlated.Results: Out of 100 women, USG detected that 54 patients (54%) had no pathology and 46 patients (46%) had abnormal findings, out of which maximum patients, 29 patients (63.04%) had endometrial hyperplasia. According to hysteroscopy, 46 patients (46%) had normal hysteroscopic findings while 54 patients (54%) had abnormal findings of which maximum were 18 patients (33.33%) who had endometrial hyperplasia. Histopathology findings revealed that 47 patients (47%) had normal findings and 53 patients (53%) had abnormal findings out of which maximum patients 20 (37.7%) had endometrial hyperplasia. In our study of 100 women with AUB, on USG only 1 patient had endometrial malignancy and the same was reported by hysteroscopy and histopathology.Conclusions: In our study hysteroscopy proved to be highly sensitive and specific considering histopathology as gold standard. Ultrasonography has good sensitivity and specificity but less as compared to hysteroscopy.

Comparative Study of Histopathology of Hysterectomy Specimen with Dilatation and Curettage and Hysteroscopic-guided Biopsy in Evaluating Perimenopausal and Postmenopausal Bleeding

“…Many researchers found that patients with positive cervical cytology have a high risk of endometrial cancer. 9 In our study, hysteroscopy detected one patient with abnormal endometrial growth which was also confirmed by histopathology giving a sensitivity of 100% which was consistent with the study done by Upadhyay et al 10…”

Correlation of Sonographic Findings and Histopathological Examination of Hysterectomy Specimens in Perimenopausal Patients with Abnormal Uterine Bleeding

“…A study carried out in Turkey also shows that most women of middle age from 31 to 40 years mostly suffer from abnormal bleeding of the uterus [13][14] . In this study, a comparison of the histopathological studies and sonographic studies was done on hysterectomy specimens were done, and most of the patients had fibroid uterus and thick endometrium walls which is exactly the results obtained in our study.…”