2023
DOI: 10.1002/jbio.202200361
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Comparative study of in‐vitro autofluorescence of normal versus non‐melanoma‐skin‐cancer cells at different excitation wavelengths

Abstract: In this experimental study the autofluorescence of squamous carcinoma cells, stimulated by 6 different excitation wavelengths in the range 280-533 nm, has been compared with the autofluorescence of normal control keratinocytes. Skin cells were cultivated in vitro, to isolate their characteristic autofluorescence form the more complex one that would be originated by the complete skin tissue. Autofluorescence spectra in the visible range were complemented by absorption measurements. It was observed that the cont… Show more

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Cited by 2 publications
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“…The tissue classification achieved an area under the receiver operating characteristic curve (AUC) of 0.82. Recent cell experiments by Garbarino et al [42] comparing SCC cells versus normal keratinocytes supported these finding revealing lower autofluorescence intensity for SCC related to FAD, NAD(P)H, lipo‐pigments, and porphyrins.…”
Section: Introductionmentioning
confidence: 83%
“…The tissue classification achieved an area under the receiver operating characteristic curve (AUC) of 0.82. Recent cell experiments by Garbarino et al [42] comparing SCC cells versus normal keratinocytes supported these finding revealing lower autofluorescence intensity for SCC related to FAD, NAD(P)H, lipo‐pigments, and porphyrins.…”
Section: Introductionmentioning
confidence: 83%